Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   BUC38_RS03485 Genome accession   NZ_LT671674
Coordinates   686427..687131 (+) Length   234 a.a.
NCBI ID   WP_044689305.1    Uniprot ID   A0A0Z8I260
Organism   Streptococcus suis strain LS9N     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 681427..692131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUC38_RS03460 - 682075..683112 (-) 1038 WP_044689302.1 acyltransferase -
  BUC38_RS03465 - 683235..683894 (-) 660 WP_009910247.1 amino acid ABC transporter permease -
  BUC38_RS03470 - 683909..684607 (-) 699 WP_004298848.1 amino acid ABC transporter permease -
  BUC38_RS03475 - 684622..685461 (-) 840 WP_044689304.1 transporter substrate-binding domain-containing protein -
  BUC38_RS03480 - 685472..686233 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  BUC38_RS03485 micA 686427..687131 (+) 705 WP_044689305.1 response regulator YycF Regulator
  BUC38_RS03490 micB 687124..688473 (+) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BUC38_RS03495 vicX 688480..689283 (+) 804 WP_044689307.1 MBL fold metallo-hydrolase Regulator
  BUC38_RS03500 vga(F) 689815..691200 (+) 1386 WP_044689309.1 ABC-F type ribosomal protection protein Vga(F) -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26824.84 Da        Isoelectric Point: 4.8135

>NTDB_id=1145991 BUC38_RS03485 WP_044689305.1 686427..687131(+) (micA) [Streptococcus suis strain LS9N]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFESEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELTETQVDLDVTGTPELIIGDLVIVPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1145991 BUC38_RS03485 WP_044689305.1 686427..687131(+) (micA) [Streptococcus suis strain LS9N]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGTCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTCGCTCGAACGATTCGTAAGACCAGCAATGTGCCAATTTTGATGTTGTCAGCC
AAAGACAGCGAGTTTGACAAGGTTATTGGTCTGGAAATTGGTGCAGATGACTATGTGACCAAGCCTTTCTCAAACCGGGA
GCTACAGGCCCGTGTCAAAGCCCTCCTTCGTCGGAGTGAATTGACAGAAACCCAGGTGGATCTTGATGTGACTGGAACGC
CAGAATTGATCATTGGTGACTTGGTGATTGTGCCGGATGCCTTTGTGGCTAAGAAGCATGGCAAAGAGCTGGAGCTTACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTAGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCCGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8I260

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

37.553

100

0.38

Multiple sequence alignment