Detailed information NTG1145992

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: BUC38_RS03490
• Genome accession: NZ_LT671674
• Coordinates: 687124..688473 (+)
• Length: 449 a.a.
• NCBI ID: WP_024379730.1
• Uniprot ID: A0A0Z8J8V5
• Organism: Streptococcus suis strain LS9N
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 682124..693473

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUC38_RS03465	-	683235..683894 (-)	660	WP_009910247.1	amino acid ABC transporter permease	-
BUC38_RS03470	-	683909..684607 (-)	699	WP_004298848.1	amino acid ABC transporter permease	-
BUC38_RS03475	-	684622..685461 (-)	840	WP_044689304.1	transporter substrate-binding domain-containing protein	-
BUC38_RS03480	-	685472..686233 (-)	762	WP_002935839.1	amino acid ABC transporter ATP-binding protein	-
BUC38_RS03485	micA	686427..687131 (+)	705	WP_044689305.1	response regulator YycF	Regulator
BUC38_RS03490	micB	687124..688473 (+)	1350	WP_024379730.1	cell wall metabolism sensor histidine kinase VicK	Regulator
BUC38_RS03495	vicX	688480..689283 (+)	804	WP_044689307.1	MBL fold metallo-hydrolase	Regulator
BUC38_RS03500	vga(F)	689815..691200 (+)	1386	WP_044689309.1	ABC-F type ribosomal protection protein Vga(F)	-
BUC38_RS03505	pbp2b	691292..693364 (+)	2073	WP_044689312.1	penicillin-binding protein PBP2B	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51035.09 Da
• Isoelectric Point: 4.5202

>NTDB_id=1145992 BUC38_RS03490 WP_024379730.1 687124..688473(+) (micB) [Streptococcus suis strain LS9N]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide

• Length: 1350 bp

>NTDB_id=1145992 BUC38_RS03490 WP_024379730.1 687124..688473(+) (micB) [Streptococcus suis strain LS9N]
ATGATTAATCAATTACGTTATTTAATGACCACAGCAGAATTTTGGTTTGTTGTCATTTTGATTGGTTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCCCTCAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGTGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCCATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTGGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (96-199)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

3D structure

• AlphaFold DB: A0A0Z8J8V5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	70.183	97.105	0.682
vicK	Streptococcus mutans UA159	70.72	89.755	0.635