Detailed information NTG1145089

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: STACADC2_RS05275
• Genome accession: NZ_LT604076
• Coordinates: 982252..982959 (-)
• Length: 235 a.a.
• NCBI ID: WP_011227274.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ACA-DC
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 977252..987959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STACADC2_RS05250 (STACADC2_0986)	yidA	977603..978412 (+)	810	WP_011226081.1	sugar-phosphatase	-
STACADC2_RS05255 (STACADC2_0987)	-	978414..979628 (+)	1215	WP_087009967.1	aminoacyltransferase	-
STACADC2_RS05260 (STACADC2_0988)	-	979680..980041 (-)	362	Protein_955	YbaN family protein	-
STACADC2_RS05265 (STACADC2_0989)	vicX	980101..980913 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
STACADC2_RS05270 (STACADC2_0990)	vicK	980919..982259 (-)	1341	WP_011227273.1	cell wall metabolism sensor histidine kinase VicK	Regulator
STACADC2_RS05275 (STACADC2_0991)	vicR	982252..982959 (-)	708	WP_011227274.1	response regulator YycF	Regulator
STACADC2_RS05280 (STACADC2_0992)	-	983485..984252 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
STACADC2_RS05285 (STACADC2_0993)	-	984264..985097 (+)	834	WP_087009968.1	transporter substrate-binding domain-containing protein	-
STACADC2_RS05290 (STACADC2_0994)	-	985115..985813 (+)	699	WP_087009969.1	amino acid ABC transporter permease	-
STACADC2_RS05295 (STACADC2_0995)	-	985825..986475 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
STACADC2_RS05300 (STACADC2_0996)	endA	986546..987427 (-)	882	WP_087009970.1	DNA/RNA non-specific endonuclease	Machinery gene
STACADC2_RS05305 (STACADC2_0997)	-	987489..987677 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27115.09 Da
• Isoelectric Point: 5.0130

>NTDB_id=1145089 STACADC2_RS05275 WP_011227274.1 982252..982959(-) (vicR) [Streptococcus thermophilus strain ACA-DC]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEIVKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1145089 STACADC2_RS05275 WP_011227274.1 982252..982959(-) (vicR) [Streptococcus thermophilus strain ACA-DC]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAATTGTCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	84.681	100	0.847
micA	Streptococcus pneumoniae Cp1015	79.399	99.149	0.787
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.136	100	0.383