Detailed information NTG1145090

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STACADC2_RS05300
• Genome accession: NZ_LT604076
• Coordinates: 986546..987427 (-)
• Length: 293 a.a.
• NCBI ID: WP_087009970.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ACA-DC
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 981546..992427

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STACADC2_RS05275 (STACADC2_0991)	vicR	982252..982959 (-)	708	WP_011227274.1	response regulator YycF	Regulator
STACADC2_RS05280 (STACADC2_0992)	-	983485..984252 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
STACADC2_RS05285 (STACADC2_0993)	-	984264..985097 (+)	834	WP_087009968.1	transporter substrate-binding domain-containing protein	-
STACADC2_RS05290 (STACADC2_0994)	-	985115..985813 (+)	699	WP_087009969.1	amino acid ABC transporter permease	-
STACADC2_RS05295 (STACADC2_0995)	-	985825..986475 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
STACADC2_RS05300 (STACADC2_0996)	endA	986546..987427 (-)	882	WP_087009970.1	DNA/RNA non-specific endonuclease	Machinery gene
STACADC2_RS05305 (STACADC2_0997)	-	987489..987677 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
STACADC2_RS05310 (STACADC2_0998)	murA	987679..988950 (-)	1272	WP_041827046.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STACADC2_RS05315 (STACADC2_0999)	-	989020..989256 (-)	237	WP_002946959.1	DUF1146 family protein	-
STACADC2_RS05320 (STACADC2_1000)	galE	989444..990457 (-)	1014	WP_087009971.1	UDP-glucose 4-epimerase GalE	-
STACADC2_RS05325 (STACADC2_1001)	-	990472..990780 (-)	309	WP_231906153.1	DUF4832 domain-containing protein	-
STACADC2_RS10030	-	990762..990926 (-)	165	WP_231906154.1	hypothetical protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31757.55 Da
• Isoelectric Point: 10.2316

>NTDB_id=1145090 STACADC2_RS05300 WP_087009970.1 986546..987427(-) (endA) [Streptococcus thermophilus strain ACA-DC]
MAKRKTSLKNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDSPIRQVASLVAGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1145090 STACADC2_RS05300 WP_087009970.1 986546..987427(-) (endA) [Streptococcus thermophilus strain ACA-DC]
ATGGCAAAAAGAAAGACATCTTTGAAAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAGTCCTATCAGACAAGTAGCAAGCCTAGTTGCAGGTAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594