Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   BJR96_RS03695 Genome accession   NZ_LT545678
Coordinates   661448..661627 (+) Length   59 a.a.
NCBI ID   WP_000965647.1    Uniprot ID   A0A837L314
Organism   Streptococcus agalactiae isolate SA111     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 619458..679586 661448..661627 within 0


Gene organization within MGE regions


Location: 619458..679586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BJR96_RS03405 (SA111_00668) - 619458..619901 (+) 444 WP_001162136.1 flavodoxin -
  BJR96_RS03410 (SA111_00669) - 619978..620253 (+) 276 WP_000418127.1 chorismate mutase -
  BJR96_RS03415 (SA111_00670) - 620246..621442 (+) 1197 WP_069986161.1 voltage-gated chloride channel family protein -
  BJR96_RS03420 (SA111_00671) tnpA 621645..622118 (+) 474 WP_070001343.1 IS200/IS605 family transposase -
  BJR96_RS03425 (SA111_00672) rplS 622773..623120 (+) 348 WP_001068667.1 50S ribosomal protein L19 -
  BJR96_RS03435 (SA111_00674) - 623345..624424 (-) 1080 WP_000264734.1 tyrosine-type recombinase/integrase -
  BJR96_RS03440 (SA111_00675) - 624547..624750 (-) 204 WP_000505363.1 hypothetical protein -
  BJR96_RS03445 (SA111_00676) - 624853..625410 (-) 558 WP_000891067.1 GTP pyrophosphokinase -
  BJR96_RS03450 (SA111_00677) - 625412..626164 (-) 753 WP_069986678.1 XRE family transcriptional regulator -
  BJR96_RS03455 (SA111_00678) - 626329..626532 (+) 204 WP_000658998.1 hypothetical protein -
  BJR96_RS03460 (SA111_00679) - 626516..626875 (-) 360 WP_000359716.1 hypothetical protein -
  BJR96_RS03465 (SA111_00680) - 626948..627136 (+) 189 WP_001166512.1 helix-turn-helix transcriptional regulator -
  BJR96_RS03470 (SA111_00681) - 627184..627933 (+) 750 WP_069986680.1 phage antirepressor KilAC domain-containing protein -
  BJR96_RS03475 (SA111_00682) - 627945..628277 (+) 333 WP_000158652.1 hypothetical protein -
  BJR96_RS03480 (SA111_00684) - 628382..628717 (-) 336 WP_000360288.1 hypothetical protein -
  BJR96_RS03485 (SA111_00685) - 628863..629048 (+) 186 WP_000263692.1 helix-turn-helix domain-containing protein -
  BJR96_RS03490 (SA111_00686) - 629127..629438 (+) 312 WP_001123481.1 hypothetical protein -
  BJR96_RS12110 (SA111_00687) - 629443..629592 (+) 150 WP_000732607.1 hypothetical protein -
  BJR96_RS03495 (SA111_00689) - 629668..629868 (+) 201 WP_001058282.1 hypothetical protein -
  BJR96_RS03500 (SA111_00690) - 629865..630155 (+) 291 WP_000650504.1 hypothetical protein -
  BJR96_RS03505 (SA111_00691) - 630142..630825 (+) 684 WP_000704951.1 AAA family ATPase -
  BJR96_RS03510 (SA111_00692) - 630831..632264 (+) 1434 Protein_613 DEAD/DEAH box helicase -
  BJR96_RS03515 (SA111_00693) - 632269..632751 (+) 483 WP_000896928.1 DUF669 domain-containing protein -
  BJR96_RS03520 (SA111_00694) - 632769..634322 (+) 1554 WP_070001311.1 phage resistance protein -
  BJR96_RS03525 (SA111_00695) - 634588..635460 (+) 873 WP_070001310.1 bifunctional DNA primase/polymerase -
  BJR96_RS03530 (SA111_00696) - 635480..635761 (+) 282 WP_032469116.1 VRR-NUC domain-containing protein -
  BJR96_RS03535 (SA111_00697) - 635840..636136 (+) 297 WP_070001309.1 nucleotide modification associated domain-containing protein -
  BJR96_RS12115 (SA111_00698) - 636120..636278 (+) 159 WP_017647865.1 hypothetical protein -
  BJR96_RS03540 (SA111_00699) - 636275..636640 (+) 366 WP_069986686.1 YopX family protein -
  BJR96_RS03545 (SA111_00700) - 636914..637348 (+) 435 WP_070001308.1 ArpU family phage packaging/lysis transcriptional regulator -
  BJR96_RS03555 - 637979..638355 (+) 377 Protein_622 HNH endonuclease -
  BJR96_RS03560 - 638506..638862 (+) 357 Protein_623 hypothetical protein -
  BJR96_RS03565 (SA111_00703) - 638859..640126 (+) 1268 Protein_624 hypothetical protein -
  BJR96_RS03570 (SA111_00704) - 640119..641339 (+) 1221 WP_000227335.1 polymorphic toxin type 50 domain-containing protein -
  BJR96_RS03575 (SA111_00705) - 641339..641527 (+) 189 WP_000421991.1 hypothetical protein -
  BJR96_RS03580 (SA111_00706) - 641635..643050 (+) 1416 WP_000256854.1 terminase large subunit -
  BJR96_RS03585 (SA111_00707) - 643131..643595 (+) 465 WP_001288696.1 capsid assembly scaffolding protein Gp46 family protein -
  BJR96_RS03590 (SA111_00708) - 643598..644500 (+) 903 WP_000841024.1 phage major capsid protein -
  BJR96_RS03595 (SA111_00709) - 644497..644712 (+) 216 WP_000640308.1 hypothetical protein -
  BJR96_RS03600 (SA111_00710) - 644726..645157 (+) 432 WP_000180799.1 phage Gp19/Gp15/Gp42 family protein -
  BJR96_RS03605 (SA111_00711) - 645108..645446 (+) 339 WP_001096306.1 hypothetical protein -
  BJR96_RS03610 (SA111_00712) - 645439..645675 (+) 237 WP_000032787.1 hypothetical protein -
  BJR96_RS03615 - 645676..646010 (+) 335 Protein_634 hypothetical protein -
  BJR96_RS03620 (SA111_00714) - 646020..646577 (+) 558 WP_000226353.1 tail protein -
  BJR96_RS03625 (SA111_00715) - 646577..646822 (+) 246 WP_069986694.1 hypothetical protein -
  BJR96_RS03630 (SA111_00716) - 646837..647187 (+) 351 WP_070005689.1 DUF5361 domain-containing protein -
  BJR96_RS03635 (SA111_00717) - 647210..649222 (+) 2013 WP_069986695.1 PblA -
  BJR96_RS03640 (SA111_00718) - 649216..650748 (+) 1533 WP_069986152.1 distal tail protein Dit -
  BJR96_RS03645 (SA111_00719) - 650749..654561 (+) 3813 WP_070005687.1 glucosaminidase domain-containing protein -
  BJR96_RS03650 (SA111_00720) - 654562..656553 (+) 1992 WP_070001270.1 DUF859 family phage minor structural protein -
  BJR96_RS03655 (SA111_00721) - 656568..656957 (+) 390 WP_070002982.1 DUF1366 domain-containing protein -
  BJR96_RS12420 - 656980..657108 (+) 129 WP_000973385.1 hypothetical protein -
  BJR96_RS03660 (SA111_00723) - 657117..657419 (+) 303 WP_001018078.1 hypothetical protein -
  BJR96_RS03665 (SA111_00724) - 657412..657639 (+) 228 WP_000609114.1 phage holin -
  BJR96_RS03670 (SA111_00726) - 657767..659110 (+) 1344 WP_069987850.1 GH25 family lysozyme -
  BJR96_RS03675 (SA111_00727) - 659476..659988 (+) 513 WP_000634506.1 PBECR4 domain-containing protein -
  BJR96_RS11855 (SA111_00728) - 660148..660347 (+) 200 Protein_648 CsbD family protein -
  BJR96_RS03685 (SA111_00729) - 660428..660679 (-) 252 WP_000455663.1 hypothetical protein -
  BJR96_RS12120 (SA111_00730) - 660820..660966 (-) 147 WP_171898157.1 hypothetical protein -
  BJR96_RS03690 (SA111_00731) - 661116..661325 (+) 210 WP_000424774.1 helix-turn-helix domain-containing protein -
  BJR96_RS03695 (SA111_00732) prx 661448..661627 (+) 180 WP_000965647.1 hypothetical protein Regulator
  BJR96_RS12430 - 661984..662307 (-) 324 WP_233263921.1 tyrosine-type recombinase/integrase -
  BJR96_RS03700 (SA111_00733) - 662343..662609 (-) 267 WP_001872365.1 hypothetical protein -
  BJR96_RS12245 - 662615..663992 (+) 1378 Protein_655 IS3 family transposase -
  BJR96_RS11465 - 664165..664326 (-) 162 WP_000508795.1 TM2 domain-containing protein -
  BJR96_RS03720 (SA111_00737) - 664534..665478 (+) 945 WP_000222594.1 IS30 family transposase -
  BJR96_RS03725 (SA111_00738) - 666119..667395 (+) 1277 Protein_658 ABC transporter permease -
  BJR96_RS03730 (SA111_00739) - 667405..668061 (+) 657 WP_000353149.1 ABC transporter ATP-binding protein -
  BJR96_RS03735 (SA111_00740) - 668061..669437 (+) 1377 WP_000594351.1 ABC transporter permease -
  BJR96_RS03740 (SA111_00741) - 669534..670187 (+) 654 WP_000699093.1 response regulator transcription factor -
  BJR96_RS03745 (SA111_00742) - 670184..671485 (+) 1302 WP_000734168.1 sensor histidine kinase -
  BJR96_RS03750 (SA111_00743) - 671537..672184 (-) 648 Protein_663 IS3 family transposase -
  BJR96_RS03755 (SA111_00744) - 672362..672541 (+) 180 WP_000076709.1 CsbD family protein -
  BJR96_RS11470 prx 672583..672771 (+) 189 WP_000027835.1 hypothetical protein Regulator
  BJR96_RS03760 (SA111_00745) - 673196..674401 (+) 1206 WP_000078931.1 FtsW/RodA/SpoVE family cell cycle protein -
  BJR96_RS03765 (SA111_00746) - 674520..675080 (+) 561 WP_001106189.1 HAD-IA family hydrolase -
  BJR96_RS03770 (SA111_00747) gyrB 675081..677033 (+) 1953 WP_000134199.1 DNA topoisomerase (ATP-hydrolyzing) subunit B -
  BJR96_RS03775 (SA111_00748) ezrA 677127..678851 (+) 1725 WP_000094341.1 septation ring formation regulator EzrA -
  BJR96_RS03780 (SA111_00749) serB 678945..679586 (+) 642 WP_000589685.1 phosphoserine phosphatase SerB -

Sequence


Protein


Download         Length: 59 a.a.        Molecular weight: 7017.06 Da        Isoelectric Point: 4.4621

>NTDB_id=1143691 BJR96_RS03695 WP_000965647.1 661448..661627(+) (prx) [Streptococcus agalactiae isolate SA111]
MLYIDEFKEAIDRGYIMGSTVAIVRKNGKIFDYVLPHEEVREEEVVTVERVEDVMRELR

Nucleotide


Download         Length: 180 bp        

>NTDB_id=1143691 BJR96_RS03695 WP_000965647.1 661448..661627(+) (prx) [Streptococcus agalactiae isolate SA111]
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAGAGGATATATTATGGGAAGCACAGTTGCGATCGTACGAAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAGAAGTGAGAGAAGAAGAGGTTGTGACAGTTGAGAGAGTGGAAGACG
TTATGAGAGAATTGAGGTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A837L314

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

74.138

98.305

0.729

  prx Streptococcus pyogenes MGAS8232

70.69

98.305

0.695

  prx Streptococcus pyogenes MGAS315

70.69

98.305

0.695

  prx Streptococcus pyogenes MGAS315

65.517

98.305

0.644

  prx Streptococcus pyogenes MGAS315

86.047

72.881

0.627

  prx Streptococcus pyogenes MGAS315

74.419

72.881

0.542

  prx Streptococcus pyogenes MGAS315

76.19

71.186

0.542


Multiple sequence alignment