Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   BJR96_RS03225 Genome accession   NZ_LT545678
Coordinates   579497..579676 (+) Length   59 a.a.
NCBI ID   WP_069986155.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate SA111     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 542157..582690 579497..579676 within 0
IScluster/Tn 580360..581705 579497..579676 flank 684


Gene organization within MGE regions


Location: 542157..582690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BJR96_RS02985 (SA111_00573) - 542175..543014 (+) 840 WP_001035227.1 SGNH/GDSL hydrolase family protein -
  BJR96_RS02990 (SA111_00574) - 542989..543591 (+) 603 WP_000806954.1 YpmS family protein -
  BJR96_RS02995 (SA111_00575) - 543694..543969 (+) 276 WP_001284634.1 HU family DNA-binding protein -
  BJR96_RS03000 (SA111_00576) - 544057..545199 (-) 1143 WP_017646861.1 tyrosine-type recombinase/integrase -
  BJR96_RS03005 (SA111_00577) - 545327..545536 (-) 210 WP_000442169.1 TM2 domain-containing protein -
  BJR96_RS03010 (SA111_00578) - 545761..546492 (-) 732 WP_070005686.1 S24 family peptidase -
  BJR96_RS03015 (SA111_00579) - 546669..546872 (+) 204 WP_000658998.1 hypothetical protein -
  BJR96_RS03020 (SA111_00580) - 546856..547215 (-) 360 WP_000359716.1 hypothetical protein -
  BJR96_RS03025 (SA111_00581) - 547288..547506 (+) 219 WP_001198775.1 helix-turn-helix transcriptional regulator -
  BJR96_RS03030 (SA111_00582) - 547518..547850 (+) 333 WP_000158652.1 hypothetical protein -
  BJR96_RS03035 (SA111_00584) - 547955..548290 (-) 336 WP_000360288.1 hypothetical protein -
  BJR96_RS03040 (SA111_00585) - 548436..548621 (+) 186 WP_000263692.1 helix-turn-helix domain-containing protein -
  BJR96_RS03045 (SA111_00586) - 548700..549011 (+) 312 WP_001123481.1 hypothetical protein -
  BJR96_RS12080 (SA111_00587) - 549016..549165 (+) 150 WP_000732607.1 hypothetical protein -
  BJR96_RS03050 (SA111_00589) - 549241..549441 (+) 201 WP_001058282.1 hypothetical protein -
  BJR96_RS03055 (SA111_00590) - 549438..549728 (+) 291 WP_000650504.1 hypothetical protein -
  BJR96_RS03060 (SA111_00591) - 549715..550398 (+) 684 WP_000704951.1 AAA family ATPase -
  BJR96_RS03065 (SA111_00592) - 550404..551837 (+) 1434 Protein_522 DEAD/DEAH box helicase -
  BJR96_RS03070 (SA111_00593) - 551842..552324 (+) 483 WP_000896928.1 DUF669 domain-containing protein -
  BJR96_RS03075 (SA111_00594) - 552342..553895 (+) 1554 WP_070001311.1 phage resistance protein -
  BJR96_RS03080 (SA111_00595) - 554161..555033 (+) 873 WP_070001310.1 bifunctional DNA primase/polymerase -
  BJR96_RS03085 (SA111_00596) - 555053..555334 (+) 282 WP_032469116.1 VRR-NUC domain-containing protein -
  BJR96_RS03090 (SA111_00597) - 555413..555709 (+) 297 WP_070001309.1 nucleotide modification associated domain-containing protein -
  BJR96_RS12085 (SA111_00598) - 555693..555851 (+) 159 WP_017647865.1 hypothetical protein -
  BJR96_RS03095 (SA111_00599) - 555848..556213 (+) 366 WP_069986686.1 YopX family protein -
  BJR96_RS03100 (SA111_00600) - 556487..556921 (+) 435 WP_070001308.1 ArpU family phage packaging/lysis transcriptional regulator -
  BJR96_RS03110 - 557551..557928 (+) 378 WP_069986158.1 HNH endonuclease -
  BJR96_RS03115 (SA111_00602) - 558079..558434 (+) 356 Protein_532 hypothetical protein -
  BJR96_RS12180 - 558431..559688 (+) 1258 Protein_533 hypothetical protein -
  BJR96_RS12105 - 559674..560898 (+) 1225 Protein_534 polymorphic toxin type 50 domain-containing protein -
  BJR96_RS03130 (SA111_00607) - 560898..561086 (+) 189 WP_000421991.1 hypothetical protein -
  BJR96_RS03135 (SA111_00608) - 561194..562609 (+) 1416 WP_000256854.1 terminase large subunit -
  BJR96_RS03140 (SA111_00609) - 562690..563154 (+) 465 WP_001288696.1 capsid assembly scaffolding protein Gp46 family protein -
  BJR96_RS03145 (SA111_00610) - 563157..564059 (+) 903 WP_000841024.1 phage major capsid protein -
  BJR96_RS03150 (SA111_00611) - 564056..564271 (+) 216 WP_000640308.1 hypothetical protein -
  BJR96_RS03155 (SA111_00612) - 564285..564716 (+) 432 WP_000180799.1 phage Gp19/Gp15/Gp42 family protein -
  BJR96_RS03160 (SA111_00613) - 564667..565005 (+) 339 WP_001096306.1 hypothetical protein -
  BJR96_RS03165 (SA111_00614) - 564998..565234 (+) 237 WP_000032787.1 hypothetical protein -
  BJR96_RS03170 (SA111_00615) - 565235..565570 (+) 336 WP_000573598.1 hypothetical protein -
  BJR96_RS12565 - 565580..566123 (+) 544 Protein_544 phage tail protein -
  BJR96_RS03180 - 566388..566761 (+) 374 Protein_545 DUF5361 domain-containing protein -
  BJR96_RS12505 - 566761..568765 (+) 2005 Protein_546 phage tail protein -
  BJR96_RS03190 (SA111_00622) - 568759..570290 (+) 1532 Protein_547 distal tail protein Dit -
  BJR96_RS03195 (SA111_00623) - 570291..574103 (+) 3813 WP_070005687.1 glucosaminidase domain-containing protein -
  BJR96_RS03200 (SA111_00624) - 574104..576095 (+) 1992 WP_070001270.1 DUF859 family phage minor structural protein -
  BJR96_RS03205 (SA111_00625) - 576110..576499 (+) 390 WP_070002982.1 DUF1366 domain-containing protein -
  BJR96_RS12405 - 576522..576650 (+) 129 WP_000973385.1 hypothetical protein -
  BJR96_RS03210 (SA111_00627) - 576659..576961 (+) 303 WP_001018078.1 hypothetical protein -
  BJR96_RS03215 (SA111_00628) - 576954..577181 (+) 228 WP_000609114.1 phage holin -
  BJR96_RS03220 (SA111_00630) - 577309..578652 (+) 1344 WP_069987850.1 GH25 family lysozyme -
  BJR96_RS11435 (SA111_00631) - 578909..579079 (-) 171 WP_000356856.1 hypothetical protein -
  BJR96_RS12410 - 579215..579340 (-) 126 WP_017285425.1 hypothetical protein -
  BJR96_RS03225 (SA111_00632) prx 579497..579676 (+) 180 WP_069986155.1 Paratox Regulator
  BJR96_RS03230 (SA111_00633) - 580082..580279 (+) 198 WP_001290370.1 hypothetical protein -
  BJR96_RS03240 (SA111_00635) - 580360..581705 (+) 1346 WP_371316017.1 IS3-like element IS861 family transposase -
  BJR96_RS03245 (SA111_00636) - 581758..582690 (-) 933 WP_000254068.1 dihydroorotate oxidase -

Sequence

Protein


Download         Length: 59 a.a.        Molecular weight: 6910.83 Da        Isoelectric Point: 4.1317

>NTDB_id=1143689 BJR96_RS03225 WP_069986155.1 579497..579676(+) (prx) [Streptococcus agalactiae isolate SA111]
MLYIDELQEAIDKGYISGNTVAIVRKNGKIFDYVLPHEEVREEEVVTVERVEDVMRELE

Nucleotide


Download         Length: 180 bp        

>NTDB_id=1143689 BJR96_RS03225 WP_069986155.1 579497..579676(+) (prx) [Streptococcus agalactiae isolate SA111]
ATGTTATATATAGATGAGCTACAAGAAGCGATTGATAAAGGCTATATTTCAGGGAACACAGTAGCGATAGTGCGTAAGAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAGAAGTGAGAGAAGAAGAGGTTGTGACAGTTGAGAGAGTGGAAGACG
TTATGAGAGAATTGGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

69.492

100

0.695
  prx Streptococcus pyogenes MGAS315

66.102

100

0.661
  prx Streptococcus pyogenes MGAS8232

67.241

98.305

0.661
  prx Streptococcus pyogenes MGAS315

83.721

72.881

0.61
  prx Streptococcus pyogenes MGAS315

60.345

98.305

0.593
  prx Streptococcus pyogenes MGAS315

71.429

71.186

0.508
  prx Streptococcus pyogenes MGAS315

69.767

72.881

0.508

Multiple sequence alignment