Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DQL00_RS11285 Genome accession   NZ_LS483523
Coordinates   2114806..2116449 (+) Length   547 a.a.
NCBI ID   WP_075575712.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836169     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2109806..2121449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL00_RS11235 blpN 2110164..2110367 (-) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  DQL00_RS11240 blpM 2110383..2110637 (-) 255 WP_000379877.1 two-peptide bacteriocin subunit BlpM -
  DQL00_RS11250 - 2111794..2112198 (-) 405 WP_000846943.1 hypothetical protein -
  DQL00_RS11255 - 2112195..2112359 (-) 165 WP_000727118.1 hypothetical protein -
  DQL00_RS11260 - 2112656..2112775 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  DQL00_RS11265 blpU 2112778..2113008 (-) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  DQL00_RS11270 blpJ 2113077..2113346 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  DQL00_RS11280 blpI 2113813..2114010 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  DQL00_RS12405 comA/nlmT 2114292..2114879 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  DQL00_RS11285 comA/nlmT 2114806..2116449 (+) 1644 WP_075575712.1 peptide cleavage/export ABC transporter Regulator
  DQL00_RS11290 - 2116460..2117821 (+) 1362 Protein_2098 bacteriocin secretion accessory protein -
  DQL00_RS11295 blpC 2117878..2118033 (+) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  DQL00_RS11300 - 2118075..2119415 (-) 1341 WP_001028044.1 sensor histidine kinase -
  DQL00_RS11305 comE/blpR 2119429..2120166 (-) 738 WP_001219147.1 response regulator transcription factor Regulator
  DQL00_RS11310 - 2120171..2120509 (-) 339 WP_000876676.1 LytTR family DNA-binding domain-containing protein -
  DQL00_RS11315 - 2120785..2121114 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61617.57 Da        Isoelectric Point: 6.5088

>NTDB_id=1142992 DQL00_RS11285 WP_075575712.1 2114806..2116449(+) (comA/nlmT) [Streptococcus pneumoniae strain 4041STDY6836169]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=1142992 DQL00_RS11285 WP_075575712.1 2114806..2116449(+) (comA/nlmT) [Streptococcus pneumoniae strain 4041STDY6836169]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGATTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGAGGCGTCTTACTGGCACAAA
ACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATATTGAATTTGATGATCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTT
AATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGT
AGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGCCACCAAGAGT
TAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(2-268)

ABC transporter (ABC_tran)

(330-479)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.711

99.817

0.726
  comA Streptococcus mitis NCTC 12261

67.276

100

0.673
  comA Streptococcus pneumoniae D39

66.91

100

0.669
  comA Streptococcus pneumoniae R6

66.91

100

0.669
  comA Streptococcus pneumoniae Rx1

66.91

100

0.669
  comA Streptococcus mitis SK321

66.728

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.606

100

0.667
  comA Streptococcus pneumoniae TIGR4

66.545

100

0.665

Multiple sequence alignment