Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DQL00_RS09210 Genome accession   NZ_LS483523
Coordinates   1726461..1727111 (-) Length   216 a.a.
NCBI ID   WP_000387336.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836169     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1721461..1732111
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL00_RS09190 - 1722066..1723247 (-) 1182 WP_000655945.1 hypothetical protein -
  DQL00_RS09195 - 1723251..1723838 (-) 588 WP_000933542.1 ATP-binding cassette domain-containing protein -
  DQL00_RS09200 - 1723870..1724058 (-) 189 WP_023396236.1 hypothetical protein -
  DQL00_RS09205 comEC/celB 1724237..1726477 (-) 2241 WP_023396235.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQL00_RS09210 comEA/celA/cilE 1726461..1727111 (-) 651 WP_000387336.1 ComEA family DNA-binding protein Machinery gene
  DQL00_RS09215 - 1727179..1727748 (-) 570 WP_000443751.1 GNAT family N-acetyltransferase -
  DQL00_RS09220 - 1727856..1728860 (-) 1005 WP_000658185.1 PhoH family protein -
  DQL00_RS09225 - 1728946..1729161 (-) 216 WP_001232085.1 YozE family protein -
  DQL00_RS09230 cvfB 1729170..1730024 (-) 855 WP_001095445.1 RNA-binding virulence regulatory protein CvfB -
  DQL00_RS09235 frr 1730084..1730641 (-) 558 WP_000024409.1 ribosome recycling factor -
  DQL00_RS09240 pyrH 1730650..1731387 (-) 738 WP_000002997.1 UMP kinase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23189.54 Da        Isoelectric Point: 5.5171

>NTDB_id=1142984 DQL00_RS09210 WP_000387336.1 1726461..1727111(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain 4041STDY6836169]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=1142984 DQL00_RS09210 WP_000387336.1 1726461..1727111(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain 4041STDY6836169]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae D39

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae R6

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

97.222

100

0.972
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.833

100

0.958
  comEA/celA/cilE Streptococcus mitis SK321

91.204

100

0.912
  comEA Lactococcus lactis subsp. cremoris KW2

43.612

100

0.458
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361

Multiple sequence alignment