Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DQL01_RS06190 Genome accession   NZ_LS483451
Coordinates   1171892..1172596 (-) Length   234 a.a.
NCBI ID   WP_000722076.1    Uniprot ID   Q9S1K0
Organism   Streptococcus pneumoniae strain 4041STDY6836166     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1166892..1177596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL01_RS06160 - 1167133..1168119 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  DQL01_RS06165 - 1168391..1169103 (-) 713 Protein_1173 potassium channel family protein -
  DQL01_RS06170 - 1169150..1169404 (-) 255 WP_044788589.1 type II toxin-antitoxin system RelE family toxin -
  DQL01_RS06175 relB 1169406..1169648 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  DQL01_RS06180 vicX 1169739..1170548 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  DQL01_RS06185 micB 1170550..1171899 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL01_RS06190 micA 1171892..1172596 (-) 705 WP_000722076.1 response regulator YycF Regulator
  DQL01_RS06195 mutY 1172651..1173826 (-) 1176 WP_000886145.1 A/G-specific adenine glycosylase -
  DQL01_RS12650 - 1173923..1174045 (+) 123 WP_256090636.1 hypothetical protein -
  DQL01_RS06200 - 1174151..1175821 (-) 1671 WP_111702564.1 formate--tetrahydrofolate ligase -
  DQL01_RS06205 coaB 1176051..1176740 (+) 690 WP_061371267.1 phosphopantothenate--cysteine ligase -
  DQL01_RS06210 coaC 1176752..1177303 (+) 552 WP_001284128.1 phosphopantothenoylcysteine decarboxylase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26815.63 Da        Isoelectric Point: 4.7164

>NTDB_id=1142058 DQL01_RS06190 WP_000722076.1 1171892..1172596(-) (micA) [Streptococcus pneumoniae strain 4041STDY6836166]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1142058 DQL01_RS06190 WP_000722076.1 1171892..1172596(-) (micA) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA
TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC
AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACGAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGTCAGGAAGCAGATAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGCGAAGAACTAGACTTAACC
CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 1NXS
  PDB 2A9O
  PDB 2A9P

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

100

100

1
  vicR Streptococcus mutans UA159

78.541

99.573

0.782
  covR Streptococcus salivarius strain HSISS4

44.156

98.718

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.478

98.291

0.427
  scnR Streptococcus mutans UA159

38.197

99.573

0.38

Multiple sequence alignment