Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   DQL01_RS06185 Genome accession   NZ_LS483451
Coordinates   1170550..1171899 (-) Length   449 a.a.
NCBI ID   WP_000886210.1    Uniprot ID   A0A064BZM9
Organism   Streptococcus pneumoniae strain 4041STDY6836166     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1165550..1176899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL01_RS06160 - 1167133..1168119 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  DQL01_RS06165 - 1168391..1169103 (-) 713 Protein_1173 potassium channel family protein -
  DQL01_RS06170 - 1169150..1169404 (-) 255 WP_044788589.1 type II toxin-antitoxin system RelE family toxin -
  DQL01_RS06175 relB 1169406..1169648 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  DQL01_RS06180 vicX 1169739..1170548 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  DQL01_RS06185 micB 1170550..1171899 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL01_RS06190 micA 1171892..1172596 (-) 705 WP_000722076.1 response regulator YycF Regulator
  DQL01_RS06195 mutY 1172651..1173826 (-) 1176 WP_000886145.1 A/G-specific adenine glycosylase -
  DQL01_RS12650 - 1173923..1174045 (+) 123 WP_256090636.1 hypothetical protein -
  DQL01_RS06200 - 1174151..1175821 (-) 1671 WP_111702564.1 formate--tetrahydrofolate ligase -
  DQL01_RS06205 coaB 1176051..1176740 (+) 690 WP_061371267.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51712.42 Da        Isoelectric Point: 4.9706

>NTDB_id=1142057 DQL01_RS06185 WP_000886210.1 1170550..1171899(-) (micB) [Streptococcus pneumoniae strain 4041STDY6836166]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1142057 DQL01_RS06185 WP_000886210.1 1170550..1171899(-) (micB) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACCAACCGTCGGGGTCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAGACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCACCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterProScan.

PAS fold (PAS)

(98-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.777

100

0.998
  vicK Streptococcus mutans UA159

69.9

89.532

0.626

Multiple sequence alignment