Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DQL12_RS02670 Genome accession   NZ_LS483450
Coordinates   495712..497388 (-) Length   558 a.a.
NCBI ID   WP_162480916.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6583227     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 490712..502388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL12_RS02640 - 491045..491374 (-) 330 WP_000132572.1 hypothetical protein -
  DQL12_RS02645 - 491650..491988 (+) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  DQL12_RS02650 comE/blpR 491993..492730 (+) 738 WP_001219120.1 response regulator transcription factor Regulator
  DQL12_RS02655 - 492744..494084 (+) 1341 WP_001017646.1 sensor histidine kinase -
  DQL12_RS02660 blpC 494155..494283 (-) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  DQL12_RS02665 - 494340..495701 (-) 1362 WP_001069075.1 bacteriocin secretion accessory protein -
  DQL12_RS02670 comA/nlmT 495712..497388 (-) 1677 WP_162480916.1 peptide cleavage/export ABC transporter Regulator
  DQL12_RS12525 comA/nlmT 497282..497869 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  DQL12_RS02675 blpI 498151..498348 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  DQL12_RS02685 blpJ 498815..499084 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  DQL12_RS02690 blpU 499153..499383 (+) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  DQL12_RS02695 - 499386..499505 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  DQL12_RS02700 - 499802..499966 (+) 165 WP_000727118.1 hypothetical protein -
  DQL12_RS02705 - 499963..500367 (+) 405 WP_000846943.1 hypothetical protein -
  DQL12_RS02710 - 500570..501374 (+) 805 WP_111695758.1 IS5 family transposase -
  DQL12_RS02715 blpM 501524..501778 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  DQL12_RS02720 blpN 501794..501997 (+) 204 WP_050255686.1 two-peptide bacteriocin subunit BlpN -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62965.24 Da        Isoelectric Point: 6.7844

>NTDB_id=1141966 DQL12_RS02670 WP_162480916.1 495712..497388(-) (comA/nlmT) [Streptococcus pneumoniae strain 4041STDY6583227]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=1141966 DQL12_RS02670 WP_162480916.1 495712..497388(-) (comA/nlmT) [Streptococcus pneumoniae strain 4041STDY6583227]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTCCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCTATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACAAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TTGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCACAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.89

99.821

0.728
  comA Streptococcus mitis NCTC 12261

67.384

100

0.674
  comA Streptococcus pneumoniae D39

67.025

100

0.67
  comA Streptococcus pneumoniae R6

67.025

100

0.67
  comA Streptococcus pneumoniae Rx1

67.025

100

0.67
  comA Streptococcus mitis SK321

66.846

100

0.668
  comA Streptococcus gordonii str. Challis substr. CH1

66.726

100

0.668
  comA Streptococcus pneumoniae TIGR4

66.667

100

0.667

Multiple sequence alignment