Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   DQK99_RS03840 Genome accession   NZ_LS483448
Coordinates   712508..713098 (+) Length   196 a.a.
NCBI ID   WP_111703781.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836167     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 711149..722159 712508..713098 within 0


Gene organization within MGE regions


Location: 711149..722159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK99_RS03830 - 711149..711616 (+) 468 WP_000136976.1 deoxycytidylate deaminase -
  DQK99_RS03835 upp 711705..712334 (+) 630 WP_000515974.1 uracil phosphoribosyltransferase -
  DQK99_RS03840 clpP 712508..713098 (+) 591 WP_111703781.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  DQK99_RS03850 - 713177..713425 (+) 249 WP_000462126.1 YlbG family protein -
  DQK99_RS03855 - 713526..714686 (+) 1161 WP_000726146.1 ABC transporter substrate-binding protein -
  DQK99_RS03860 - 714954..715823 (+) 870 WP_000941421.1 branched-chain amino acid ABC transporter permease -
  DQK99_RS03865 - 715827..716783 (+) 957 WP_000662293.1 branched-chain amino acid ABC transporter permease -
  DQK99_RS03870 - 716783..717547 (+) 765 WP_001186003.1 ABC transporter ATP-binding protein -
  DQK99_RS03875 - 717547..718257 (+) 711 WP_000062220.1 ABC transporter ATP-binding protein -
  DQK99_RS03880 - 718671..719327 (+) 657 WP_000268654.1 CBS domain-containing protein -
  DQK99_RS03885 prfB 719435..720530 (+) 1096 WP_099975370.1 peptide chain release factor 2 -
  DQK99_RS03890 ftsE 720548..721240 (+) 693 WP_000022268.1 cell division ATP-binding protein FtsE -
  DQK99_RS03895 ftsX 721233..722159 (+) 927 WP_000625536.1 permease-like cell division protein FtsX -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21416.39 Da        Isoelectric Point: 4.4204

>NTDB_id=1141814 DQK99_RS03840 WP_111703781.1 712508..713098(+) (clpP) [Streptococcus pneumoniae strain 4041STDY6836167]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSDQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide


Download         Length: 591 bp        

>NTDB_id=1141814 DQK99_RS03840 WP_111703781.1 712508..713098(+) (clpP) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACGAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGGACTGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGATCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

99.49

100

0.995
  clpP Streptococcus pneumoniae D39

99.49

100

0.995
  clpP Streptococcus pneumoniae R6

99.49

100

0.995
  clpP Streptococcus pneumoniae TIGR4

99.49

100

0.995
  clpP Streptococcus thermophilus LMG 18311

92.308

99.49

0.918
  clpP Streptococcus thermophilus LMD-9

92.308

99.49

0.918
  clpP Streptococcus pyogenes JRS4

90.256

99.49

0.898
  clpP Streptococcus pyogenes MGAS315

90.256

99.49

0.898
  clpP Streptococcus mutans UA159

85.204

100

0.852
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

85.128

99.49

0.847
  clpP Lactococcus lactis subsp. cremoris KW2

84.615

99.49

0.842
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.031

98.469

0.571
  clpP Bacillus subtilis subsp. subtilis str. 168

58.333

97.959

0.571

Multiple sequence alignment