Detailed information NTG1141715

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: DQL20_RS01305
• Genome accession: NZ_LS483444
• Coordinates: 217145..217597 (+)
• Length: 150 a.a.
• NCBI ID: WP_040803180.1
• Uniprot ID: -
• Organism: Streptococcus australis strain NCTC13166
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 212145..222597

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL20_RS01270 (NCTC11371_00252)	-	212496..213599 (+)	1104	WP_006595140.1	glycosyl hydrolase family 8	-
DQL20_RS01275 (NCTC11371_00253)	-	213806..214183 (+)	378	WP_006595139.1	DUF1033 family protein	-
DQL20_RS01280 (NCTC11371_00254)	comYA	214289..215230 (+)	942	WP_006597118.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL20_RS01285 (NCTC11371_00255)	comYB	215163..216194 (+)	1032	WP_408022506.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL20_RS01290 (NCTC11371_00256)	comGC/cglC	216191..216508 (+)	318	WP_006595136.1	competence type IV pilus major pilin ComGC	Machinery gene
DQL20_RS01295	comGD	216477..216902 (+)	426	WP_040802795.1	competence type IV pilus minor pilin ComGD	-
DQL20_RS01300 (NCTC11371_00258)	comGE	216868..217161 (+)	294	WP_006595134.1	competence type IV pilus minor pilin ComGE	-
DQL20_RS01305 (NCTC11371_00259)	comGF/cglF	217145..217597 (+)	453	WP_040803180.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL20_RS01310 (NCTC11371_00260)	comGG	217563..218009 (+)	447	WP_006595132.1	competence type IV pilus minor pilin ComGG	-
DQL20_RS01315 (NCTC11371_00261)	comYH	218041..218994 (+)	954	WP_006597125.1	class I SAM-dependent methyltransferase	Machinery gene
DQL20_RS01320 (NCTC11371_00262)	-	219043..220239 (+)	1197	WP_006595130.1	acetate kinase	-
DQL20_RS01325 (NCTC11371_00263)	-	220385..221074 (+)	690	WP_006595129.1	CPBP family intramembrane glutamic endopeptidase	-
DQL20_RS01330 (NCTC11371_00264)	folP	221234..222190 (+)	957	WP_023022082.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 150 a.a.
• Molecular weight: 17207.81 Da
• Isoelectric Point: 5.0874

>NTDB_id=1141715 DQL20_RS01305 WP_040803180.1 217145..217597(+) (comGF/cglF) [Streptococcus australis strain NCTC13166]
MLKRTKLPAFTLLEALVALLVISGGLLVFQGLTSLLRQELQYQSHIKQEEWLLFQDQLDIELSRSQFEEVRDNKFYLVQD
QKPIAIGLAKGGDIRKTDATGRGYQPMIDGVESARIEKRGDLVSIQLRFEEGLEREVVYRVVEKDKKEAD

Nucleotide

• Length: 453 bp

>NTDB_id=1141715 DQL20_RS01305 WP_040803180.1 217145..217597(+) (comGF/cglF) [Streptococcus australis strain NCTC13166]
CTGTTGAAAAGAACTAAACTGCCAGCCTTTACTTTACTGGAGGCCTTGGTTGCCCTGCTCGTCATCAGCGGTGGTTTATT
GGTGTTTCAAGGATTGACAAGCCTTTTGCGTCAAGAACTCCAGTACCAAAGTCACATCAAGCAAGAGGAATGGTTGCTCT
TTCAGGACCAGCTGGACATTGAATTGTCTCGTAGCCAATTTGAAGAGGTCAGAGATAACAAATTCTATCTTGTTCAGGAT
CAAAAACCCATAGCCATTGGACTGGCTAAGGGGGGAGATATCCGAAAGACAGATGCGACTGGCCGTGGCTATCAACCGAT
GATAGATGGAGTTGAATCCGCCAGGATTGAAAAAAGAGGAGATCTGGTGTCTATTCAACTGCGCTTTGAAGAAGGGTTAG
AAAGGGAGGTGGTCTACCGTGTGGTGGAAAAGGATAAAAAAGAAGCAGATTGA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	56.944	96	0.547
comGF/cglF	Streptococcus pneumoniae D39	56.944	96	0.547
comGF/cglF	Streptococcus pneumoniae R6	56.944	96	0.547
comGF/cglF	Streptococcus pneumoniae TIGR4	56.944	96	0.547
comGF/cglF	Streptococcus mitis NCTC 12261	55.396	92.667	0.513
comGF/cglF	Streptococcus mitis SK321	55.396	92.667	0.513
comYF	Streptococcus mutans UA159	41.379	96.667	0.4
comYF	Streptococcus mutans UA140	41.379	96.667	0.4