Detailed information
Bioinformatically predicted
Overview
| Name | clpP | Type | Regulator |
| Locus tag | DQN54_RS03665 | Genome accession | NZ_LS483417 |
| Coordinates | 680267..680857 (+) | Length | 196 a.a. |
| NCBI ID | WP_000613477.1 | Uniprot ID | A0A064BX72 |
| Organism | Streptococcus pneumoniae strain NCTC11902 | ||
| Function | degradation of ComX; degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 650972..715364 | 680267..680857 | within | 0 |
Gene organization within MGE regions
Location: 650972..715364
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DQN54_RS03495 (NCTC11902_00658) | - | 651399..651533 (+) | 135 | Protein_660 | lactate oxidase | - |
| DQN54_RS03500 (NCTC11902_00659) | lysS | 651673..653163 (+) | 1491 | WP_000102461.1 | lysine--tRNA ligase | - |
| DQN54_RS03510 (NCTC11902_00660) | lctO | 653787..654923 (+) | 1137 | WP_000120721.1 | L-lactate oxidase | - |
| DQN54_RS03515 (NCTC11902_00662) | - | 655480..656148 (+) | 669 | WP_000449824.1 | TenA family protein | - |
| DQN54_RS11985 | - | 656203..656334 (-) | 132 | WP_001819092.1 | hypothetical protein | - |
| DQN54_RS03525 (NCTC11902_00663) | thiM | 656437..657219 (+) | 783 | WP_000202472.1 | hydroxyethylthiazole kinase | - |
| DQN54_RS03530 (NCTC11902_00664) | thiE | 657221..657850 (+) | 630 | WP_000468578.1 | thiamine phosphate synthase | - |
| DQN54_RS03540 (NCTC11902_00666) | - | 658409..658969 (+) | 561 | WP_000915286.1 | ECF transporter S component | - |
| DQN54_RS03545 (NCTC11902_00667) | - | 658970..660355 (+) | 1386 | WP_000522118.1 | ATP-binding cassette domain-containing protein | - |
| DQN54_RS03550 (NCTC11902_00668) | - | 660357..661007 (+) | 651 | WP_000241371.1 | energy-coupling factor transporter transmembrane component T | - |
| DQN54_RS03555 (NCTC11902_00669) | tenA | 661018..661710 (+) | 693 | WP_000397220.1 | thiaminase II | - |
| DQN54_RS03560 (NCTC11902_00670) | thiW | 661715..662239 (+) | 525 | WP_001225556.1 | energy coupling factor transporter S component ThiW | - |
| DQN54_RS03565 (NCTC11902_00671) | - | 662239..663042 (+) | 804 | WP_001148663.1 | hydroxyethylthiazole kinase | - |
| DQN54_RS03570 (NCTC11902_00672) | thiE | 663035..663667 (+) | 633 | WP_001078226.1 | thiamine phosphate synthase | - |
| DQN54_RS03575 (NCTC11902_00673) | thiD | 663877..664668 (-) | 792 | WP_000221739.1 | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | - |
| DQN54_RS03580 (NCTC11902_00675) | - | 665034..665429 (+) | 396 | WP_001167218.1 | CopY/TcrY family copper transport repressor | - |
| DQN54_RS03585 (NCTC11902_00676) | - | 665440..665811 (+) | 372 | WP_000935064.1 | cupredoxin domain-containing protein | - |
| DQN54_RS03590 (NCTC11902_00677) | - | 665821..668064 (+) | 2244 | WP_000136303.1 | heavy metal translocating P-type ATPase | - |
| DQN54_RS03595 (NCTC11902_00678) | spxB | 668271..670046 (+) | 1776 | WP_000191795.1 | pyruvate oxidase | - |
| DQN54_RS03600 (NCTC11902_00679) | - | 670157..670504 (+) | 348 | WP_001052655.1 | VOC family protein | - |
| DQN54_RS03605 | - | 670621..671532 (-) | 912 | Protein_680 | IS630 family transposase | - |
| DQN54_RS03610 (NCTC11902_00682) | - | 671918..672223 (+) | 306 | Protein_681 | family 1 glycosylhydrolase | - |
| DQN54_RS03615 (NCTC11902_00683) | manA | 672355..673299 (+) | 945 | WP_001294318.1 | mannose-6-phosphate isomerase, class I | - |
| DQN54_RS03620 (NCTC11902_00684) | - | 673321..674796 (-) | 1476 | WP_001813257.1 | sodium-dependent transporter | - |
| DQN54_RS03630 (NCTC11902_00685) | - | 674879..675633 (+) | 755 | Protein_684 | MerR family transcriptional regulator | - |
| DQN54_RS03635 (NCTC11902_00686) | - | 675653..676108 (-) | 456 | WP_001823744.1 | 8-oxo-dGTP diphosphatase | - |
| DQN54_RS03640 (NCTC11902_00687) | - | 676128..677303 (-) | 1176 | WP_000680053.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| DQN54_RS03645 (NCTC11902_00688) | - | 677362..678207 (-) | 846 | WP_000219939.1 | DegV family protein | - |
| DQN54_RS03650 (NCTC11902_00689) | - | 678332..678889 (+) | 558 | WP_000004139.1 | TetR/AcrR family transcriptional regulator | - |
| DQN54_RS03655 (NCTC11902_00690) | - | 678908..679375 (+) | 468 | WP_000136976.1 | deoxycytidylate deaminase | - |
| DQN54_RS03660 (NCTC11902_00691) | upp | 679464..680093 (+) | 630 | WP_001812010.1 | uracil phosphoribosyltransferase | - |
| DQN54_RS03665 (NCTC11902_00692) | clpP | 680267..680857 (+) | 591 | WP_000613477.1 | ATP-dependent Clp protease proteolytic subunit ClpP | Regulator |
| DQN54_RS03675 (NCTC11902_00693) | - | 680936..681184 (+) | 249 | WP_000462126.1 | YlbG family protein | - |
| DQN54_RS03680 (NCTC11902_00694) | - | 681285..682445 (+) | 1161 | WP_000726139.1 | ABC transporter substrate-binding protein | - |
| DQN54_RS03685 (NCTC11902_00695) | - | 682713..683582 (+) | 870 | WP_000941426.1 | branched-chain amino acid ABC transporter permease | - |
| DQN54_RS03690 (NCTC11902_00696) | - | 683586..684542 (+) | 957 | WP_000662293.1 | branched-chain amino acid ABC transporter permease | - |
| DQN54_RS03695 (NCTC11902_00697) | - | 684542..685306 (+) | 765 | WP_001186003.1 | ABC transporter ATP-binding protein | - |
| DQN54_RS03700 (NCTC11902_00698) | - | 685306..686016 (+) | 711 | WP_000062219.1 | ABC transporter ATP-binding protein | - |
| DQN54_RS03705 (NCTC11902_00699) | - | 686481..687137 (+) | 657 | WP_000268652.1 | CBS domain-containing protein | - |
| DQN54_RS03710 (NCTC11902_00700) | prfB | 687245..688340 (+) | 1096 | WP_015511312.1 | peptide chain release factor 2 | - |
| DQN54_RS03715 (NCTC11902_00701) | ftsE | 688358..689050 (+) | 693 | WP_000022265.1 | cell division ATP-binding protein FtsE | - |
| DQN54_RS03720 (NCTC11902_00702) | ftsX | 689043..689969 (+) | 927 | WP_000625536.1 | permease-like cell division protein FtsX | - |
| DQN54_RS03725 (NCTC11902_00703) | - | 690390..691343 (+) | 954 | WP_001155321.1 | IS30-like element ISSpn8 family transposase | - |
| DQN54_RS03730 (NCTC11902_00704) | - | 691500..693680 (+) | 2181 | WP_000974080.1 | PTS transporter subunit IIBC | - |
| DQN54_RS03735 (NCTC11902_00705) | - | 693732..694547 (+) | 816 | WP_000670830.1 | endonuclease/exonuclease/phosphatase family protein | - |
| DQN54_RS03740 (NCTC11902_00706) | - | 694687..696030 (+) | 1344 | WP_000011011.1 | DEAD/DEAH box helicase | - |
| DQN54_RS03745 (NCTC11902_00707) | metK | 696245..697435 (+) | 1191 | WP_000003935.1 | methionine adenosyltransferase | - |
| DQN54_RS03755 (NCTC11902_00708) | - | 697988..698923 (+) | 936 | WP_000255160.1 | dihydroorotate oxidase | - |
| DQN54_RS03760 (NCTC11902_00709) | holA | 698957..699994 (+) | 1038 | WP_000879655.1 | DNA polymerase III subunit delta | - |
| DQN54_RS03765 (NCTC11902_00710) | sodA | 700167..700772 (+) | 606 | WP_000974746.1 | superoxide dismutase SodA | - |
| DQN54_RS03770 (NCTC11902_00711) | - | 700928..701458 (+) | 531 | WP_001224352.1 | YutD family protein | - |
| DQN54_RS03775 (NCTC11902_00712) | rlmN | 701479..702564 (+) | 1086 | WP_000804641.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| DQN54_RS03780 (NCTC11902_00713) | - | 702564..703040 (+) | 477 | WP_000976711.1 | VanZ family protein | - |
| DQN54_RS03785 (NCTC11902_00714) | - | 703042..704583 (+) | 1542 | WP_000025400.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| DQN54_RS03790 (NCTC11902_00715) | - | 704639..705442 (-) | 804 | WP_000731918.1 | peptidylprolyl isomerase | - |
| DQN54_RS03795 (NCTC11902_00716) | - | 705526..705738 (-) | 213 | WP_000011696.1 | hypothetical protein | - |
| DQN54_RS03805 | - | 706217..706426 (-) | 210 | WP_000953865.1 | hypothetical protein | - |
| DQN54_RS03810 (NCTC11902_00717) | rpsP | 706596..706868 (+) | 273 | WP_000268761.1 | 30S ribosomal protein S16 | - |
| DQN54_RS03815 (NCTC11902_00718) | kphA | 706888..707127 (+) | 240 | WP_000379621.1 | RNA-binding protein KphA | - |
| DQN54_RS11700 | - | 707288..707599 (+) | 312 | Protein_719 | MazG nucleotide pyrophosphohydrolase domain-containing protein | - |
| DQN54_RS03825 (NCTC11902_00719) | - | 707703..708452 (+) | 750 | WP_000819199.1 | alpha/beta hydrolase | - |
| DQN54_RS03830 (NCTC11902_00720) | rimM | 708522..709040 (+) | 519 | WP_001105898.1 | ribosome maturation factor RimM | - |
| DQN54_RS03835 (NCTC11902_00721) | trmD | 709030..709749 (+) | 720 | WP_000686921.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| DQN54_RS03840 (NCTC11902_00722) | - | 709761..710099 (+) | 339 | WP_001196049.1 | ATP cone domain-containing protein | - |
| DQN54_RS03845 (NCTC11902_00723) | - | 710130..710450 (-) | 321 | WP_001216099.1 | hypothetical protein | - |
| DQN54_RS03850 (NCTC11902_00724) | - | 710548..710763 (+) | 216 | WP_000807422.1 | YdbC family protein | - |
| DQN54_RS11705 (NCTC11902_00725) | - | 710760..710906 (-) | 147 | WP_001809980.1 | hypothetical protein | - |
| DQN54_RS03860 (NCTC11902_00726) | - | 710968..711504 (-) | 537 | WP_000709049.1 | biotin transporter BioY | - |
| DQN54_RS03865 (NCTC11902_00727) | - | 711930..712268 (+) | 339 | WP_000746105.1 | hypothetical protein | - |
| DQN54_RS03870 (NCTC11902_00728) | - | 712334..714316 (+) | 1983 | WP_000768911.1 | hypothetical protein | - |
| DQN54_RS03875 (NCTC11902_00729) | - | 714313..714936 (+) | 624 | WP_000151029.1 | ATP-binding cassette domain-containing protein | - |
Sequence
Protein
Download Length: 196 a.a. Molecular weight: 21358.36 Da Isoelectric Point: 4.4910
>NTDB_id=1140863 DQN54_RS03665 WP_000613477.1 680267..680857(+) (clpP) [Streptococcus pneumoniae strain NCTC11902]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
Nucleotide
Download Length: 591 bp
>NTDB_id=1140863 DQN54_RS03665 WP_000613477.1 680267..680857(+) (clpP) [Streptococcus pneumoniae strain NCTC11902]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpP | Streptococcus pneumoniae Rx1 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae D39 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae R6 |
100 |
100 |
1 |
| clpP | Streptococcus pneumoniae TIGR4 |
100 |
100 |
1 |
| clpP | Streptococcus thermophilus LMG 18311 |
92.821 |
99.49 |
0.923 |
| clpP | Streptococcus thermophilus LMD-9 |
92.821 |
99.49 |
0.923 |
| clpP | Streptococcus pyogenes JRS4 |
90.769 |
99.49 |
0.903 |
| clpP | Streptococcus pyogenes MGAS315 |
90.769 |
99.49 |
0.903 |
| clpP | Streptococcus mutans UA159 |
85.714 |
100 |
0.857 |
| clpP | Lactococcus lactis subsp. lactis strain DGCC12653 |
85.128 |
99.49 |
0.847 |
| clpP | Lactococcus lactis subsp. cremoris KW2 |
84.615 |
99.49 |
0.842 |
| clpP | Bacillus subtilis subsp. subtilis str. 168 |
58.854 |
97.959 |
0.577 |
| clpP | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.031 |
98.469 |
0.571 |