Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQN40_RS03125 Genome accession   NZ_LS483413
Coordinates   586706..587416 (+) Length   236 a.a.
NCBI ID   WP_084916255.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 581706..592416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN40_RS03100 (NCTC7136_00638) - 582385..583380 (+) 996 WP_084916252.1 DUF3114 domain-containing protein -
  DQN40_RS03105 (NCTC7136_00639) - 583476..584123 (-) 648 WP_003057245.1 amino acid ABC transporter permease -
  DQN40_RS03110 (NCTC7136_00640) - 584138..584839 (-) 702 WP_003057191.1 amino acid ABC transporter permease -
  DQN40_RS03115 (NCTC7136_00641) - 584853..585653 (-) 801 WP_003057243.1 transporter substrate-binding domain-containing protein -
  DQN40_RS03120 (NCTC7136_00642) - 585653..586447 (-) 795 WP_084916254.1 amino acid ABC transporter ATP-binding protein -
  DQN40_RS03125 (NCTC7136_00643) vicR 586706..587416 (+) 711 WP_084916255.1 response regulator YycF Regulator
  DQN40_RS03130 (NCTC7136_00644) vicK 587409..588761 (+) 1353 WP_084916257.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQN40_RS03135 (NCTC7136_00645) vicX 588765..589574 (+) 810 WP_003059746.1 MBL fold metallo-hydrolase Regulator
  DQN40_RS03140 (NCTC7136_00646) rnc 590332..591024 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27004.90 Da        Isoelectric Point: 4.9038

>NTDB_id=1140697 DQN40_RS03125 WP_084916255.1 586706..587416(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGCEAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1140697 DQN40_RS03125 WP_084916255.1 586706..587416(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGATGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGTCTTGAAATTGGGGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCTCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

37.712

100

0.377

Multiple sequence alignment