Detailed information NTG1140698

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: DQN40_RS03130
• Genome accession: NZ_LS483413
• Coordinates: 587409..588761 (+)
• Length: 450 a.a.
• NCBI ID: WP_084916257.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 582409..593761

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN40_RS03105 (NCTC7136_00639)	-	583476..584123 (-)	648	WP_003057245.1	amino acid ABC transporter permease	-
DQN40_RS03110 (NCTC7136_00640)	-	584138..584839 (-)	702	WP_003057191.1	amino acid ABC transporter permease	-
DQN40_RS03115 (NCTC7136_00641)	-	584853..585653 (-)	801	WP_003057243.1	transporter substrate-binding domain-containing protein	-
DQN40_RS03120 (NCTC7136_00642)	-	585653..586447 (-)	795	WP_084916254.1	amino acid ABC transporter ATP-binding protein	-
DQN40_RS03125 (NCTC7136_00643)	vicR	586706..587416 (+)	711	WP_084916255.1	response regulator YycF	Regulator
DQN40_RS03130 (NCTC7136_00644)	vicK	587409..588761 (+)	1353	WP_084916257.1	cell wall metabolism sensor histidine kinase VicK	Regulator
DQN40_RS03135 (NCTC7136_00645)	vicX	588765..589574 (+)	810	WP_003059746.1	MBL fold metallo-hydrolase	Regulator
DQN40_RS03140 (NCTC7136_00646)	rnc	590332..591024 (+)	693	WP_003057240.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51550.14 Da
• Isoelectric Point: 5.5741

>NTDB_id=1140698 DQN40_RS03130 WP_084916257.1 587409..588761(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSYKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKFYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=1140698 DQN40_RS03130 WP_084916257.1 587409..588761(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
ATGACTAGAGATATCATTGGAAACTTGTCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCTATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAAGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACGCCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTTATCAAGGTTTCTCTTGATGAAACTAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGTTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-165)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	72.947	92	0.671
micB	Streptococcus pneumoniae Cp1015	66.588	94.444	0.629