Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQN21_RS09120 Genome accession   NZ_LS483409
Coordinates   1830123..1830833 (-) Length   236 a.a.
NCBI ID   WP_009854646.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1825123..1835833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS09105 (NCTC13773_01852) rnc 1826776..1827462 (-) 687 WP_009854642.1 ribonuclease III -
  DQN21_RS09110 (NCTC13773_01853) vicX 1827968..1828777 (-) 810 WP_009854644.1 MBL fold metallo-hydrolase Regulator
  DQN21_RS09115 (NCTC13773_01854) vicK 1828778..1830130 (-) 1353 WP_077497391.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQN21_RS09120 (NCTC13773_01855) vicR 1830123..1830833 (-) 711 WP_009854646.1 response regulator YycF Regulator
  DQN21_RS09125 (NCTC13773_01856) - 1831134..1831898 (+) 765 WP_009854647.1 amino acid ABC transporter ATP-binding protein -
  DQN21_RS09130 (NCTC13773_01857) - 1831909..1832721 (+) 813 WP_077497393.1 transporter substrate-binding domain-containing protein -
  DQN21_RS09135 (NCTC13773_01858) - 1832738..1833442 (+) 705 WP_009854649.1 amino acid ABC transporter permease -
  DQN21_RS09140 (NCTC13773_01859) - 1833454..1834101 (+) 648 WP_009854650.1 amino acid ABC transporter permease -
  DQN21_RS09145 (NCTC13773_01860) - 1834193..1834801 (-) 609 WP_009854651.1 TVP38/TMEM64 family protein -
  DQN21_RS09150 (NCTC13773_01861) - 1835049..1835351 (-) 303 WP_009854652.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27150.94 Da        Isoelectric Point: 4.6512

>NTDB_id=1140579 DQN21_RS09120 WP_009854646.1 1830123..1830833(-) (vicR) [Streptococcus gallolyticus strain NCTC13773]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAITKFEEEDPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIETAVAEENASASNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1140579 DQN21_RS09120 WP_009854646.1 1830123..1830833(-) (vicR) [Streptococcus gallolyticus strain NCTC13773]
ATGAAAAAAATTCTTATCGTTGATGATGAAAAACCAATTTCGGATATTATTAAATTTAATTTAACTAAAGAAGGTTATGA
AACCGTAACGGCTTTTGATGGTCGTGAAGCTATTACAAAGTTTGAGGAAGAAGATCCAGATTTGATTATCTTGGATTTGA
TGTTGCCAGAATTGGACGGACTTGAAGTGGCTAAAGAAGTTCGCAAGACAAGTCATATTCCAATCATTATGTTGTCTGCT
AAGGATAGCGAGTTTGATAAAGTTATCGGACTTGAAATTGGTGCAGATGACTATGTAACCAAACCATTTTCAAATCGTGA
ATTGTTGGCGCGTGTTAAAGCGCACCTTCGTCGTACAGAAAATATTGAAACAGCAGTTGCTGAAGAAAATGCTTCTGCTT
CAAATTCAGAAATCACAATTGGCGACTTGAAAATTTTACCAGATGCCTTTGTGGCACAAAAACGTGGTGAAGATATCGAA
TTGACACACCGTGAGTTTGAATTGCTACATCATTTGGCAACACATATGGGACAAGTCATGACCCGTGAATATCTTTTGGA
AACCGTTTGGGGCTATGATTATTTTGGTGATGTGCGTACGGTTGACGTAACGATTCGTCGTTTACGTGAAAAAATCGAAG
ACACACCAAGCCGTCCAGAATATATTTTGACACGTCGTGGTGTTGGGTACTACATGAAGTCATATGAATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

89.831

100

0.898
  micA Streptococcus pneumoniae Cp1015

77.778

99.153

0.771
  covR Streptococcus salivarius strain HSISS4

47.845

98.305

0.47
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.121

98.305

0.453
  scnR Streptococcus mutans UA159

37.288

100

0.373

Multiple sequence alignment