Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DQN21_RS09115 Genome accession   NZ_LS483409
Coordinates   1828778..1830130 (-) Length   450 a.a.
NCBI ID   WP_077497391.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1823778..1835130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS09105 (NCTC13773_01852) rnc 1826776..1827462 (-) 687 WP_009854642.1 ribonuclease III -
  DQN21_RS09110 (NCTC13773_01853) vicX 1827968..1828777 (-) 810 WP_009854644.1 MBL fold metallo-hydrolase Regulator
  DQN21_RS09115 (NCTC13773_01854) vicK 1828778..1830130 (-) 1353 WP_077497391.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQN21_RS09120 (NCTC13773_01855) vicR 1830123..1830833 (-) 711 WP_009854646.1 response regulator YycF Regulator
  DQN21_RS09125 (NCTC13773_01856) - 1831134..1831898 (+) 765 WP_009854647.1 amino acid ABC transporter ATP-binding protein -
  DQN21_RS09130 (NCTC13773_01857) - 1831909..1832721 (+) 813 WP_077497393.1 transporter substrate-binding domain-containing protein -
  DQN21_RS09135 (NCTC13773_01858) - 1832738..1833442 (+) 705 WP_009854649.1 amino acid ABC transporter permease -
  DQN21_RS09140 (NCTC13773_01859) - 1833454..1834101 (+) 648 WP_009854650.1 amino acid ABC transporter permease -
  DQN21_RS09145 (NCTC13773_01860) - 1834193..1834801 (-) 609 WP_009854651.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51548.59 Da        Isoelectric Point: 4.6944

>NTDB_id=1140578 DQN21_RS09115 WP_077497391.1 1828778..1830130(-) (vicK) [Streptococcus gallolyticus strain NCTC13773]
MNDTMLQNLTYFEQAILFLLAFVAVYFVYLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELADQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRAGNITMINQTAQQQLNLEREEALQMNIVDILGSDSTYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIVVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTISGKQYEIVRDYPIKS
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSEIYDEWEDEEE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1140578 DQN21_RS09115 WP_077497391.1 1828778..1830130(-) (vicK) [Streptococcus gallolyticus strain NCTC13773]
ATGAATGATACAATGTTACAAAATTTAACTTATTTTGAACAAGCCATTCTCTTTCTTTTAGCATTTGTCGCAGTTTATTT
TGTTTATTTAGCGATAAGAGATTATCGAACTTCTGTTAATATTCGACGTTTGAGTGGTAAAGTGCGAGAGCTTATCACAG
GAAAATACACAGAAGATATTATTATTGAAAAAGATAGAGACTTAGCTGAGTTAGCTGACCAATTAAATGATTTGTCAACA
GTCTTTCGTTTAGCGCAGGAAAATTTGGCACAAGAAAAGAATCGTTTGGCGAGTATCTTATCTTATATGACAGACGGTGT
CTTGGCGACTGACCGTGCTGGAAATATCACAATGATTAATCAGACCGCGCAACAACAACTCAATTTAGAGCGTGAAGAAG
CTTTGCAGATGAATATTGTTGATATTTTGGGTTCTGATAGCACTTATAGTTATCATGATTTGGTGTCAAAAACACCTGAA
ATTGTCTTGAACCGTCGTGACGAAACAGGTGAATTTATCACTTTACGTATTCGCTTTGCTCTAAATCGTCGTGATAGTGG
CTTTATTTCAGGGTTGATTGTTGTTTTGCATGACACAACCGAACAAGAAAAAGAAGACCGTGAGCGTCGTCTTTTCGTTT
CTAACGTTAGTCATGAATTGCGAACACCATTAACATCTGTAAAATCTTATCTGGAAGCTTTAGATGAAGGAGCGCTCAAA
GAAGACATTGCGCCAAGTTTTATCAAAGTATCTTTAGATGAAACAAACCGCATGATTCGTATGATTTCAGACTTGCTTAA
TTTATCGCGTATTGATAATCAGACGGTTCAATTGGAAGTGGAAATGACAAATTTCACAGCATTTATGACATCAATTCTTA
ACCGTTTTGATCAAATTAAAAGCCAACATACAATCAGCGGAAAACAGTATGAGATTGTCAGGGATTATCCTATTAAATCA
ATCTGGCTTGAAATTGACCCTGATAAGATGACGCAGGTTTTGGATAATATCCTTAATAATGCTATCAAATATTCACCAGA
TGGTGGAAAAATCACAGTTAGCATGAAAACGACGGAAACACAGTTGATTATCTCAATCTCTGATGAAGGGCTTGGTATTC
CTAAGAAAGATTTGCCATTGATTTTCGACCGTTTCTATCGTGTGGATAAGGCTCGAAGTCGTGCCCAAGGTGGTTCAGGA
CTTGGCTTAGCTATCGCAAAAGAAATTGTCAAACAACATAAAGGTTTTATTTGGGCACAAAGTACTTACGGAAAAGGGTC
GACCTTTACGATTGTACTTCCTTACGAAAAAGATTCTGAAATTTATGATGAATGGGAGGATGAAGAAGAGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

PAS fold (PAS)

(95-189)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

75.422

92.222

0.696
  micB Streptococcus pneumoniae Cp1015

65.802

94.222

0.62

Multiple sequence alignment