Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   DQN21_RS06150 Genome accession   NZ_LS483409
Coordinates   1208435..1209277 (-) Length   280 a.a.
NCBI ID   WP_074657162.1    Uniprot ID   A0A1I7HX35
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1203435..1214277
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS06130 (NCTC13773_01242) - 1204168..1204650 (-) 483 WP_061459342.1 hypothetical protein -
  DQN21_RS06135 (NCTC13773_01243) - 1204667..1205386 (-) 720 WP_077496857.1 DUF3307 domain-containing protein -
  DQN21_RS06140 (NCTC13773_01244) - 1205386..1206051 (-) 666 WP_039693668.1 SatD family protein -
  DQN21_RS06145 (NCTC13773_01245) topA 1206199..1208340 (-) 2142 WP_077496859.1 type I DNA topoisomerase -
  DQN21_RS06150 (NCTC13773_01246) dprA 1208435..1209277 (-) 843 WP_074657162.1 DNA-processing protein DprA Machinery gene
  DQN21_RS06155 (NCTC13773_01247) - 1209350..1209901 (-) 552 WP_009854204.1 sugar O-acetyltransferase -
  DQN21_RS06160 (NCTC13773_01248) - 1209903..1210682 (-) 780 WP_077496861.1 ribonuclease HII -
  DQN21_RS06165 (NCTC13773_01249) ylqF 1210669..1211523 (-) 855 WP_064593005.1 ribosome biogenesis GTPase YlqF -
  DQN21_RS06170 (NCTC13773_01250) - 1211767..1212177 (+) 411 WP_077496862.1 DUF4231 domain-containing protein -
  DQN21_RS06175 (NCTC13773_01251) - 1212387..1212704 (-) 318 WP_077496864.1 hypothetical protein -
  DQN21_RS06180 (NCTC13773_01252) - 1212688..1212876 (-) 189 WP_077496866.1 hypothetical protein -
  DQN21_RS12590 - 1212881..1213030 (-) 150 WP_014294551.1 hypothetical protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 30912.96 Da        Isoelectric Point: 8.5553

>NTDB_id=1140563 DQN21_RS06150 WP_074657162.1 1208435..1209277(-) (dprA) [Streptococcus gallolyticus strain NCTC13773]
MNNFELFKLKKAGLTNLNILAILDYQEKQEKSLSLRNMAVVSKCKNPILFMEKYKALDTKELRKEFNCFPSVSILDDEYP
LELKHCYNPPVLLFYQGNLELLNRPKMAVVGARTASATGTKSVQKIVKELGNHFVIVSGLARGIDTSAHLSALKNGGASI
AVIGCGLDVYYPKENKQLQAYMAKNHLVLSEYVAGEAPLKFHFPERNRIIAGLSQGVIVVEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCVTSGLDILSEYQI

Nucleotide


Download         Length: 843 bp        

>NTDB_id=1140563 DQN21_RS06150 WP_074657162.1 1208435..1209277(-) (dprA) [Streptococcus gallolyticus strain NCTC13773]
ATGAATAATTTTGAATTGTTTAAATTAAAAAAAGCAGGATTAACAAATCTTAATATTTTAGCTATTTTAGATTATCAAGA
AAAGCAAGAGAAATCACTATCTTTGCGTAATATGGCAGTCGTCTCAAAATGTAAAAATCCTATCCTTTTTATGGAAAAAT
ACAAAGCACTGGACACCAAAGAATTGCGCAAAGAATTTAATTGTTTTCCTAGTGTTTCCATACTAGATGACGAATACCCA
TTAGAACTCAAACATTGTTATAATCCACCTGTTTTGCTGTTTTATCAAGGAAATTTAGAATTACTTAATCGCCCAAAAAT
GGCAGTAGTAGGAGCAAGAACAGCATCAGCAACAGGGACAAAATCCGTACAGAAAATTGTCAAAGAACTCGGGAATCATT
TTGTTATCGTTAGTGGGTTGGCGCGTGGCATTGATACCAGTGCGCATTTATCAGCTCTAAAAAACGGTGGTGCATCGATT
GCCGTTATCGGTTGCGGACTGGACGTTTATTATCCCAAAGAAAATAAGCAGTTGCAGGCGTACATGGCTAAAAATCACCT
CGTATTAAGTGAGTACGTAGCAGGAGAAGCACCGCTGAAATTCCATTTTCCAGAGCGAAATCGTATTATTGCAGGGCTAT
CACAAGGCGTTATCGTAGTAGAAGCTAAGCTGCGCTCAGGCAGTTTGATTACGTGTGAAAGAGCATTGGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGAAATATTTTAGATGGAAAATCTGATGGCTGTCATCATTTGATAAAAGAGGGCGCAAAATG
CGTCACATCAGGCTTAGATATCCTTTCGGAATATCAAATATAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I7HX35

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

74.46

99.286

0.739
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

64.286

100

0.643
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

64.286

100

0.643
  dprA/cilB/dalA Streptococcus pneumoniae D39

64.286

100

0.643
  dprA/cilB/dalA Streptococcus pneumoniae R6

64.286

100

0.643
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

64.286

100

0.643
  dprA/cilB/dalA Streptococcus mitis SK321

64.286

100

0.643
  dprA Lactococcus lactis subsp. cremoris KW2

62.23

99.286

0.618
  dprA Legionella pneumophila strain ERS1305867

42.324

86.071

0.364
  dprA Haemophilus influenzae Rd KW20

38.636

94.286

0.364

Multiple sequence alignment