Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQN33_RS03070 Genome accession   NZ_LS483408
Coordinates   578509..579219 (+) Length   236 a.a.
NCBI ID   WP_015912156.1    Uniprot ID   -
Organism   Streptococcus uberis strain NCTC4674     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 573509..584219
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN33_RS03045 (NCTC4674_00628) - 574229..575236 (+) 1008 WP_111673119.1 DUF3114 domain-containing protein -
  DQN33_RS03050 (NCTC4674_00629) - 575267..575914 (-) 648 WP_012658074.1 amino acid ABC transporter permease -
  DQN33_RS03055 (NCTC4674_00630) - 575930..576631 (-) 702 WP_012658075.1 amino acid ABC transporter permease -
  DQN33_RS03060 (NCTC4674_00631) - 576646..577461 (-) 816 WP_012658076.1 transporter substrate-binding domain-containing protein -
  DQN33_RS03065 (NCTC4674_00632) - 577475..578254 (-) 780 WP_012658077.1 amino acid ABC transporter ATP-binding protein -
  DQN33_RS03070 (NCTC4674_00633) vicR 578509..579219 (+) 711 WP_015912156.1 response regulator YycF Regulator
  DQN33_RS03075 (NCTC4674_00634) vicK 579212..580570 (+) 1359 WP_012658078.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQN33_RS03080 (NCTC4674_00635) vicX 580574..581383 (+) 810 WP_046393354.1 MBL fold metallo-hydrolase Regulator
  DQN33_RS03085 (NCTC4674_00636) rnc 581542..582234 (+) 693 WP_012658080.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26983.91 Da        Isoelectric Point: 5.0023

>NTDB_id=1140499 DQN33_RS03070 WP_015912156.1 578509..579219(+) (vicR) [Streptococcus uberis strain NCTC4674]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGKEAVLAFEEEKPDLVILDLMLPEMDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIESAVAEENASAGSQELTIGNLQILPDAFLAKKYGKEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSHD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1140499 DQN33_RS03070 WP_015912156.1 578509..579219(+) (vicR) [Streptococcus uberis strain NCTC4674]
ATGAAAAAAATTCTTATCGTGGATGATGAAAAACCCATCTCTGATATTATCAAGTTTAATTTAACCAAGGAAGGCTATGA
CATTGTGACAGCTTTCGATGGTAAAGAAGCGGTTCTTGCTTTTGAGGAAGAAAAGCCTGACTTAGTGATTTTGGATTTGA
TGTTACCAGAAATGGATGGTTTAGAAGTCGCCAAAGAAATTCGTAAAACCAGTCATATTCCTATCATTATGCTTTCAGCT
AAAGACAGTGAATTTGATAAGGTTATCGGATTAGAAATTGGGGCCGATGACTACGTCACAAAACCTTTCTCTAATCGTGA
ATTATTGGCACGTGTAAAAGCGCATTTGCGAAGGACCGAAACTATTGAATCAGCGGTAGCAGAGGAAAATGCGTCTGCAG
GCAGTCAAGAGTTGACTATCGGTAATTTACAAATATTGCCGGATGCCTTTTTAGCCAAAAAATATGGAAAAGAAGTTGAA
TTAACCCATCGTGAATTTGAGCTTTTACATCATTTGGCCAACCACATTGGTCAGGTCATGACACGTGAGCACCTTTTAGA
AACAGTATGGGGTTATGATTATTTTGGAGATGTGCGTACTGTTGACGTGACAGTTCGTCGCCTAAGAGAAAAAATAGAAG
ATACACCAAGCCGTCCGGAATACATTTTGACAAGACGTGGCGTTGGCTATTACATGAAATCACATGACTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.559

100

0.886
  micA Streptococcus pneumoniae Cp1015

77.447

99.576

0.771
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.534

98.305

0.428
  scnR Streptococcus mutans UA159

38.197

98.729

0.377

Multiple sequence alignment