Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQN23_RS06445 Genome accession   NZ_LS483403
Coordinates   1283627..1284337 (-) Length   236 a.a.
NCBI ID   WP_039696509.1    Uniprot ID   A0A6G8HYC0
Organism   Streptococcus lutetiensis strain NCTC13774     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1278627..1289337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN23_RS06430 (NCTC13774_01340) rnc 1280565..1281251 (-) 687 WP_020917219.1 ribonuclease III -
  DQN23_RS06435 (NCTC13774_01341) vicX 1281472..1282281 (-) 810 WP_058814132.1 MBL fold metallo-hydrolase Regulator
  DQN23_RS06440 (NCTC13774_01342) vicK 1282282..1283634 (-) 1353 WP_111712942.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQN23_RS06445 (NCTC13774_01343) vicR 1283627..1284337 (-) 711 WP_039696509.1 response regulator YycF Regulator
  DQN23_RS06450 (NCTC13774_01344) - 1284649..1285407 (+) 759 WP_020917223.1 amino acid ABC transporter ATP-binding protein -
  DQN23_RS06455 (NCTC13774_01345) - 1285424..1286236 (+) 813 WP_020917224.1 transporter substrate-binding domain-containing protein -
  DQN23_RS06460 (NCTC13774_01346) - 1286252..1286959 (+) 708 WP_020917225.1 amino acid ABC transporter permease -
  DQN23_RS06465 (NCTC13774_01347) - 1286972..1287619 (+) 648 WP_111712943.1 amino acid ABC transporter permease -
  DQN23_RS06470 (NCTC13774_01348) - 1287656..1288264 (-) 609 WP_111712944.1 TVP38/TMEM64 family protein -
  DQN23_RS06475 (NCTC13774_01349) - 1288476..1288778 (-) 303 WP_020917228.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27121.90 Da        Isoelectric Point: 4.7040

>NTDB_id=1140360 DQN23_RS06445 WP_039696509.1 1283627..1284337(-) (vicR) [Streptococcus lutetiensis strain NCTC13774]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAIAKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASSSNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1140360 DQN23_RS06445 WP_039696509.1 1283627..1284337(-) (vicR) [Streptococcus lutetiensis strain NCTC13774]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCAATTTCAGATATTATTAAATTTAATTTAACTAAAGAAGGTTATGA
AACTGTTACGGCTTTTGATGGTCGTGAAGCTATTGCTAAATTTGAAGAAGAAAATCCTGATTTGATTATCTTGGATTTGA
TGTTGCCAGAATTGGATGGACTTGAAGTTGCAAAAGAAGTTCGTAAAACAAGTCATATTCCGATTATTATGCTTTCTGCT
AAAGATAGCGAATTCGATAAAGTTATCGGTCTTGAAATCGGTGCAGATGACTATGTTACAAAACCTTTCTCAAATCGTGA
ATTGTTAGCACGTGTCAAAGCACACCTTCGTCGTACTGAGAACATCGAATCAGCCGTCGCTGAGGAAAATGCTTCTTCAT
CAAATTCTGAAATTACCATCGGCGATTTGAAGATTTTGCCTGATGCCTTTGTTGCTCAAAAACGTGGTGAAGACATCGAA
TTAACACACCGTGAATTTGAATTACTTCATCACTTAGCTACTCACATGGGACAAGTGATGACGCGTGAATACCTTCTGGA
AACTGTTTGGGGTTATGATTACTTTGGTGATGTCCGCACAGTTGACGTTACCATTCGTCGTTTGCGTGAAAAAATCGAAG
ACACTCCGAGTCGTCCAGAATACATTTTGACACGTCGCGGTGTTGGATACTACATGAAGTCTTATGAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8HYC0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

78.205

99.153

0.775
  covR Streptococcus salivarius strain HSISS4

46.983

98.305

0.462
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.69

98.305

0.449
  scnR Streptococcus mutans UA159

36.441

100

0.364

Multiple sequence alignment