Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DQN23_RS06440 Genome accession   NZ_LS483403
Coordinates   1282282..1283634 (-) Length   450 a.a.
NCBI ID   WP_111712942.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC13774     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1277282..1288634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN23_RS06430 (NCTC13774_01340) rnc 1280565..1281251 (-) 687 WP_020917219.1 ribonuclease III -
  DQN23_RS06435 (NCTC13774_01341) vicX 1281472..1282281 (-) 810 WP_058814132.1 MBL fold metallo-hydrolase Regulator
  DQN23_RS06440 (NCTC13774_01342) vicK 1282282..1283634 (-) 1353 WP_111712942.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQN23_RS06445 (NCTC13774_01343) vicR 1283627..1284337 (-) 711 WP_039696509.1 response regulator YycF Regulator
  DQN23_RS06450 (NCTC13774_01344) - 1284649..1285407 (+) 759 WP_020917223.1 amino acid ABC transporter ATP-binding protein -
  DQN23_RS06455 (NCTC13774_01345) - 1285424..1286236 (+) 813 WP_020917224.1 transporter substrate-binding domain-containing protein -
  DQN23_RS06460 (NCTC13774_01346) - 1286252..1286959 (+) 708 WP_020917225.1 amino acid ABC transporter permease -
  DQN23_RS06465 (NCTC13774_01347) - 1286972..1287619 (+) 648 WP_111712943.1 amino acid ABC transporter permease -
  DQN23_RS06470 (NCTC13774_01348) - 1287656..1288264 (-) 609 WP_111712944.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51377.36 Da        Isoelectric Point: 4.7779

>NTDB_id=1140359 DQN23_RS06440 WP_111712942.1 1282282..1283634(-) (vicK) [Streptococcus lutetiensis strain NCTC13774]
MNDTMVQNQYLFEQAILFLLAFVAIYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQKQLNLEREEALGMNIVDILGDDSDYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWVEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDNED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1140359 DQN23_RS06440 WP_111712942.1 1282282..1283634(-) (vicK) [Streptococcus lutetiensis strain NCTC13774]
ATGAATGATACAATGGTACAGAATCAATATCTGTTTGAACAAGCCATTCTCTTCTTGCTAGCTTTTGTAGCCATTTATTT
TATTCATTTGGCTATCAGAGACTATAGAACGTCTGTTAATATTCGTCGATTAAGTGGTAAGGTTCGTGAACTGATTACAG
GAAAATACACAGAAGATATTATCATTGAAAAAGACAGAGATTTAGCAGAGTTAGCTGGTCAGTTAAATGATTTGTCAACT
GTCTTTCGTTTAGCTCAAGAAAATCTAGCCCAAGAAAAGAATCGTTTGGCAAGTATTTTGTCTTACATGACTGATGGGGT
GCTAGCGACTGACCGTTCTGGAAATATCACCATGATTAACCAGACCGCTCAAAAGCAACTAAATCTTGAGCGTGAAGAAG
CTCTTGGGATGAATATCGTTGACATTCTTGGTGATGATAGCGATTATTCTTACCATGATTTGGTGTCTAAGACGCCAGAA
ATTGTGCTTAATCGTCGTGATGAGACGGGAGAATTTATCACTTTGCGTATTCGATTTGCCTTGAATCGTAGAGATAGTGG
ATTTATTTCTGGTCTGATTGCCGTCTTGCACGATACAACGGAACAAGAAAAAGAAGACCGCGAACGTCGCTTGTTCGTTT
CTAACGTTAGTCATGAGTTGCGTACGCCACTGACTTCGGTTAAATCTTATCTTGAAGCACTGGATGAAGGGGCTTTGAAA
GAAGATATTGCACCAAGTTTCATCAAAGTTTCTTTGGATGAAACCAATCGTATGATTCGCATGATTTCTGATTTGCTTAA
TCTGTCTCGAATCGACAATCAAACGGTGCAATTAGAAGTTGAAATGACTAACTTCACAGCCTTTATGACGTCTATTTTGA
ATCGTTTTGACCAGATTAAAAGTCAACACACGGTTGCTGGCAAGCAATACGAAATTGTCAGAGACTATCCAATCAAGTCA
ATCTGGGTTGAAATTGACCCAGATAAGATGACACAAGTCTTGGATAATATCCTAAACAATGCCATTAAGTACTCACCAGA
CGGTGGTAAAATCACTGTTAGCATGAAGACAACTGAAACTCAGTTGATTATTTCGATTTCTGATGAAGGACTTGGTATTC
CGAAGAAAGACTTGCCGTTAATCTTTGACCGTTTCTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGTTCAGGG
CTTGGACTTGCCATTGCTAAAGAAATTGTCAAACAACATAAAGGATTTATTTGGGCTCAAAGTACCTATGGTAAGGGCTC
AACATTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGATGAATGGGAGGATAACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.867

92.222

0.709
  micB Streptococcus pneumoniae Cp1015

64.237

97.556

0.627

Multiple sequence alignment