Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM37_RS07625 Genome accession   NZ_LS483394
Coordinates   1501155..1501706 (-) Length   183 a.a.
NCBI ID   WP_111694966.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC10880     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1496155..1506706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM37_RS07600 (NCTC10880_01516) - 1497521..1498366 (+) 846 WP_002982833.1 mechanosensitive ion channel family protein -
  DQM37_RS07605 (NCTC10880_01517) - 1498431..1498991 (-) 561 WP_002995157.1 TIGR01440 family protein -
  DQM37_RS07610 (NCTC10880_01518) - 1499005..1499475 (-) 471 WP_002988139.1 ECF transporter S component -
  DQM37_RS07615 (NCTC10880_01519) - 1499465..1500229 (-) 765 WP_002988136.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  DQM37_RS07620 (NCTC10880_01520) truA 1500219..1500968 (-) 750 WP_002988132.1 tRNA pseudouridine(38-40) synthase TruA -
  DQM37_RS07625 (NCTC10880_01521) comX/sigX/comX2/sigX2 1501155..1501706 (-) 552 WP_111694966.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22208.08 Da        Isoelectric Point: 10.2770

>NTDB_id=1140111 DQM37_RS07625 WP_111694966.1 1501155..1501706(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC10880]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLKRYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGGVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=1140111 DQM37_RS07625 WP_111694966.1 1501155..1501706(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC10880]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAAAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGGGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.361

100

0.984
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.361

100

0.984
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.361

100

0.984
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.361

100

0.984
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

44.805

84.153

0.377
  comX/sigX Streptococcus mutans UA159

42.5

87.432

0.372

Multiple sequence alignment