Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM81_RS08445 Genome accession   NZ_LS483389
Coordinates   1624437..1624988 (-) Length   183 a.a.
NCBI ID   WP_111688228.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC10879     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1619437..1629988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM81_RS08410 (NCTC10879_01688) - 1619441..1620184 (-) 744 WP_038433909.1 class I SAM-dependent DNA methyltransferase -
  DQM81_RS08415 (NCTC10879_01689) rsfS 1620232..1620585 (-) 354 WP_011017339.1 ribosome silencing factor -
  DQM81_RS08420 (NCTC10879_01690) yqeK 1620609..1621202 (-) 594 WP_038433908.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DQM81_RS08425 (NCTC10879_01691) - 1621199..1621831 (-) 633 WP_038433907.1 nicotinate-nucleotide adenylyltransferase -
  DQM81_RS08430 (NCTC10879_01692) yhbY 1621900..1622208 (-) 309 WP_002991094.1 ribosome assembly RNA-binding protein YhbY -
  DQM81_RS08435 (NCTC10879_01693) yqeH 1622233..1623351 (-) 1119 WP_015016688.1 ribosome biogenesis GTPase YqeH -
  DQM81_RS08440 (NCTC10879_01694) - 1623351..1623878 (-) 528 WP_002991099.1 YqeG family HAD IIIA-type phosphatase -
  DQM81_RS08445 (NCTC10879_01695) comX/sigX/comX2/sigX2 1624437..1624988 (-) 552 WP_111688228.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22307.16 Da        Isoelectric Point: 10.0375

>NTDB_id=1139871 DQM81_RS08445 WP_111688228.1 1624437..1624988(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC10879]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNLQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=1139871 DQM81_RS08445 WP_111688228.1 1624437..1624988(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC10879]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTTGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAAGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.333

81.967

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment