Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM81_RS01490 Genome accession   NZ_LS483389
Coordinates   273899..274450 (+) Length   183 a.a.
NCBI ID   WP_111688228.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC10879     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 268899..279450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM81_RS01490 (NCTC10879_00295) comX/sigX/comX2/sigX2 273899..274450 (+) 552 WP_111688228.1 sigma-70 family RNA polymerase sigma factor Regulator
  DQM81_RS01495 (NCTC10879_00296) truA 274635..275384 (+) 750 WP_002988132.1 tRNA pseudouridine(38-40) synthase TruA -
  DQM81_RS01500 (NCTC10879_00297) - 275374..276138 (+) 765 WP_002988136.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  DQM81_RS01505 (NCTC10879_00298) - 276128..276598 (+) 471 WP_002988139.1 ECF transporter S component -
  DQM81_RS01510 (NCTC10879_00299) - 276612..277172 (+) 561 WP_002988142.1 TIGR01440 family protein -
  DQM81_RS01515 (NCTC10879_00300) - 277237..278082 (-) 846 WP_002982833.1 mechanosensitive ion channel family protein -

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22307.16 Da        Isoelectric Point: 10.0375

>NTDB_id=1139842 DQM81_RS01490 WP_111688228.1 273899..274450(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC10879]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNLQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=1139842 DQM81_RS01490 WP_111688228.1 273899..274450(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC10879]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTTGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAAGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.333

81.967

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment