Detailed information NTG1139806

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: DQM45_RS07490
• Genome accession: NZ_LS483388
• Coordinates: 1507170..1507760 (-)
• Length: 196 a.a.
• NCBI ID: WP_003083781.1
• Uniprot ID: A0A4V0H7V7
• Organism: Streptococcus porcinus strain NCTC10999
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1502170..1512760

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM45_RS07460 (NCTC10999_01518)	-	1502221..1502985 (-)	765	WP_003084650.1	ABC transporter ATP-binding protein	-
DQM45_RS07465 (NCTC10999_01519)	-	1502986..1503939 (-)	954	WP_003084871.1	branched-chain amino acid ABC transporter permease	-
DQM45_RS07470 (NCTC10999_01520)	-	1503942..1504811 (-)	870	WP_003083303.1	branched-chain amino acid ABC transporter permease	-
DQM45_RS07475 (NCTC10999_01521)	-	1504854..1506026 (-)	1173	WP_003084401.1	ABC transporter substrate-binding protein	-
DQM45_RS07480 (NCTC10999_01522)	-	1506188..1506436 (-)	249	WP_003082879.1	DUF2129 domain-containing protein	-
DQM45_RS07485 (NCTC10999_01523)	-	1506406..1506882 (-)	477	WP_003086116.1	YlbF family regulator	-
DQM45_RS07490 (NCTC10999_01524)	clpP	1507170..1507760 (-)	591	WP_003083781.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
DQM45_RS07495 (NCTC10999_01525)	upp	1507986..1508615 (-)	630	WP_003084317.1	uracil phosphoribosyltransferase	-
DQM45_RS07500 (NCTC10999_01526)	-	1508844..1510478 (-)	1635	WP_003085017.1	polysaccharide biosynthesis protein	-
DQM45_RS07505 (NCTC10999_01527)	-	1510565..1512022 (+)	1458	WP_003082548.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21743.01 Da
• Isoelectric Point: 4.8856

>NTDB_id=1139806 DQM45_RS07490 WP_003083781.1 1507170..1507760(-) (clpP) [Streptococcus porcinus strain NCTC10999]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGAGSGTQQTDMAIVAEQLLKTRKRLEKILADNSGK
TIKQIHKDAERDYWMDAKETLEYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=1139806 DQM45_RS07490 WP_003083781.1 1507170..1507760(-) (clpP) [Streptococcus porcinus strain NCTC10999]
ATGATTCCTGTAGTTATTGAACAAACAAGTCGAGGAGAACGTTCTTATGATATCTATTCACGTCTCCTAAAAGACCGTAT
TATTATGCTGACTGGACCAGTTGAAGATAATATGGCAAATTCTATTATTGCACAATTGTTATTTTTGGACGCGCAAGATA
ATACTAAAGATATTTACCTCTATGTAAATACACCTGGAGGTTCAGTTTCAGCTGGTCTAGCAATTGTTGATACTATGAAC
TTTATTAAATCAGATGTTCAAACTATTGTAATGGGTATGGCTGCCTCAATGGGAACTATCATTGCATCATCAGGTGCCAA
AGGCAAACGATTCATGCTACCAAATGCTGAATACTTAATTCATCAACCGATGGGTGGTGCTGGCAGTGGTACGCAACAAA
CGGATATGGCAATTGTTGCTGAACAGTTGTTAAAAACACGGAAACGTCTTGAAAAAATCCTTGCTGATAATTCTGGTAAG
ACGATTAAACAAATTCATAAAGATGCAGAACGTGACTACTGGATGGATGCCAAAGAGACTTTAGAATATGGCTTCATTGA
TGAAATTATGGAAAATAATGAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A4V0H7V7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	94.898	100	0.949
clpP	Streptococcus pyogenes JRS4	92.347	100	0.923
clpP	Streptococcus pyogenes MGAS315	92.347	100	0.923
clpP	Lactococcus lactis subsp. cremoris KW2	91.837	100	0.918
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	91.327	100	0.913
clpP	Streptococcus thermophilus LMD-9	89.286	100	0.893
clpP	Streptococcus thermophilus LMG 18311	89.286	100	0.893
clpP	Streptococcus pneumoniae Rx1	87.692	99.49	0.872
clpP	Streptococcus pneumoniae D39	87.692	99.49	0.872
clpP	Streptococcus pneumoniae R6	87.692	99.49	0.872
clpP	Streptococcus pneumoniae TIGR4	87.692	99.49	0.872
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.513	98.469	0.566
clpP	Bacillus subtilis subsp. subtilis str. 168	56.122	100	0.561