Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM82_RS01545 Genome accession   NZ_LS483386
Coordinates   282393..282944 (+) Length   183 a.a.
NCBI ID   WP_080262832.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC13742     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 277393..287944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM82_RS01545 (NCTC13742_00305) comX/sigX/comX2/sigX2 282393..282944 (+) 552 WP_080262832.1 competence protein ComX Regulator
  DQM82_RS01550 (NCTC13742_00306) - 283525..284052 (+) 528 WP_002991099.1 YqeG family HAD IIIA-type phosphatase -
  DQM82_RS01555 (NCTC13742_00307) yqeH 284052..285170 (+) 1119 WP_023612142.1 ribosome biogenesis GTPase YqeH -
  DQM82_RS01560 (NCTC13742_00308) yhbY 285195..285503 (+) 309 WP_023612138.1 ribosome assembly RNA-binding protein YhbY -
  DQM82_RS01565 (NCTC13742_00309) - 285572..286204 (+) 633 WP_011184179.1 nicotinate-nucleotide adenylyltransferase -
  DQM82_RS01570 (NCTC13742_00310) yqeK 286201..286794 (+) 594 WP_023612141.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DQM82_RS01575 (NCTC13742_00311) rsfS 286818..287171 (+) 354 WP_032465567.1 ribosome silencing factor -

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22280.14 Da        Isoelectric Point: 10.1972

>NTDB_id=1139686 DQM82_RS01545 WP_080262832.1 282393..282944(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC13742]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLKRYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=1139686 DQM82_RS01545 WP_080262832.1 282393..282944(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC13742]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAAAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAAGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

45.455

84.153

0.383
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment