Detailed information NTG1139577

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQM87_RS04445
• Genome accession: NZ_LS483384
• Coordinates: 868316..869152 (-)
• Length: 278 a.a.
• NCBI ID: WP_111705052.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13743
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 863316..874152

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM87_RS04420 (NCTC13743_00881)	-	863536..864528 (-)	993	WP_047235809.1	D-lactate dehydrogenase	-
DQM87_RS04425 (NCTC13743_00882)	-	864543..865109 (-)	567	Protein_794	PTS sugar transporter subunit IIC	-
DQM87_RS09425	-	865149..866006 (+)	858	Protein_795	LysR family transcriptional regulator	-
DQM87_RS04440 (NCTC13743_00884)	topA	866081..868210 (-)	2130	WP_111705051.1	type I DNA topoisomerase	-
DQM87_RS04445 (NCTC13743_00885)	dprA	868316..869152 (-)	837	WP_111705052.1	DNA-processing protein DprA	Machinery gene
DQM87_RS04450 (NCTC13743_00886)	-	869217..870008 (-)	792	WP_111705053.1	ribonuclease HII	-
DQM87_RS04455 (NCTC13743_00887)	ylqF	869998..870846 (-)	849	WP_111705054.1	ribosome biogenesis GTPase YlqF	-
DQM87_RS04460 (NCTC13743_00888)	-	871065..871505 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DQM87_RS04465 (NCTC13743_00889)	trhA	871502..872152 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DQM87_RS04470 (NCTC13743_00890)	-	872269..873180 (+)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
DQM87_RS04475 (NCTC13743_00891)	-	873230..873670 (-)	441	WP_009880949.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31009.02 Da
• Isoelectric Point: 9.2511

>NTDB_id=1139577 DQM87_RS04445 WP_111705052.1 868316..869152(-) (dprA) [Streptococcus pyogenes strain NCTC13743]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIETYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=1139577 DQM87_RS04445 WP_111705052.1 868316..869152(-) (dprA) [Streptococcus pyogenes strain NCTC13743]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAACCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367
dprA	Acinetobacter baumannii D1279779	37.828	96.043	0.363