Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   DQM67_RS10220 Genome accession   NZ_LS483383
Coordinates   1995663..1997009 (-) Length   448 a.a.
NCBI ID   WP_376738740.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1990663..2002009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS10185 (NCTC12479_01974) - 1991329..1992123 (+) 795 WP_005591388.1 energy-coupling factor transporter transmembrane protein EcfT -
  DQM67_RS10595 (NCTC12479_01975) - 1992310..1992969 (+) 660 WP_005591387.1 LysM peptidoglycan-binding domain-containing protein -
  DQM67_RS10195 (NCTC12479_01976) sdaAA 1993025..1993897 (-) 873 WP_005591386.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  DQM67_RS10200 (NCTC12479_01977) sdaAB 1993906..1994577 (-) 672 WP_005592070.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  DQM67_RS10215 (NCTC12479_01980) comE/comE2 1994923..1995666 (-) 744 WP_005591384.1 competence system response regulator transcription factor ComE Regulator
  DQM67_RS10220 (NCTC12479_01981) comD/comD1 1995663..1997009 (-) 1347 WP_376738740.1 sensor histidine kinase Regulator
  DQM67_RS10225 (NCTC12479_01982) comC 1997032..1997160 (-) 129 WP_005591382.1 bacteriocin Regulator
  DQM67_RS10235 (NCTC12479_01984) rlmH 1997455..1997934 (-) 480 WP_005591381.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DQM67_RS10240 (NCTC12479_01985) htrA 1998137..1999315 (+) 1179 WP_005591380.1 S1C family serine protease Regulator
  DQM67_RS10245 (NCTC12479_01986) spo0J 1999378..2000139 (+) 762 WP_005591379.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 448 a.a.        Molecular weight: 53323.43 Da        Isoelectric Point: 5.3880

>NTDB_id=1139542 DQM67_RS10220 WP_376738740.1 1995663..1997009(-) (comD/comD1) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MMFELFFWILQAAIEVYFTIVIYEKINKVKSSFYFTFLCAIVLILLPLLILNLESIFSLSRHVLYFILLLIYPLFFYRYF
YKKEKLSTLFSIFLSLLLYLTVQSSTTFFSVIISSITGDSFVKDNWVVFYIMINSISVLFMLKFIDYLPFYACDFKEEVF
KKTIKRINIFYVIDIFILNVSHWLSEDDHFNSFSSMLATICFLIFMTTLFYLKAIREKYEKEEEIRQRELEQLQLQQYTD
EIVSLYNEIRGFRHDYAGMLTSFQMAINTQDIKEIEKIYQEVLVDANLKLRSDKYTYFDLNNVGDSALRSVMTETLFKAR
EHQIDLTFEVKDPVEKLPIKLLDVVRMASILLNNAVEGAIESYEKMIHVTLVQLDTEIIFVVKNSRKQRKLDLEEIYEPE
FSTKGYRRGLGLNNLKEILENYEYIMLDTEISKYDFTQVLTIKRRNSL

Nucleotide


Download         Length: 1347 bp        

>NTDB_id=1139542 DQM67_RS10220 WP_376738740.1 1995663..1997009(-) (comD/comD1) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATTATGTTTGAATTATTTTTTTGGATATTGCAAGCCGCCATTGAAGTATATTTCACTATTGTTATATATGAAAAGATAAA
TAAAGTAAAATCTAGTTTTTACTTTACTTTTCTGTGTGCTATAGTCTTAATTTTATTACCATTACTCATATTAAATTTAG
AATCTATATTTTCTTTGTCAAGGCATGTTCTGTATTTTATTTTACTACTGATTTATCCTCTTTTTTTCTACAGATATTTT
TATAAAAAAGAGAAGTTATCAACTCTTTTCTCTATATTTCTATCTCTTCTCCTTTATTTAACAGTTCAGTCTTCTACTAC
CTTTTTTTCCGTCATTATTTCCTCAATTACAGGGGATTCATTTGTAAAAGATAATTGGGTTGTCTTTTATATCATGATAA
ACAGTATCTCTGTTCTATTTATGCTTAAGTTTATCGACTACTTACCATTTTACGCATGTGATTTTAAAGAGGAGGTCTTT
AAAAAGACAATTAAGAGAATTAATATTTTTTATGTTATAGATATTTTCATTTTAAATGTTTCTCATTGGTTAAGTGAAGA
CGATCATTTTAATAGTTTTAGCAGTATGCTAGCGACTATTTGTTTCTTGATCTTTATGACAACTCTTTTCTATTTGAAGG
CAATTCGGGAAAAGTATGAAAAAGAAGAGGAGATTCGACAAAGAGAATTGGAACAGTTGCAGCTGCAGCAGTATACAGAT
GAAATTGTTTCTCTCTATAATGAAATTCGTGGTTTTCGTCATGATTATGCCGGCATGCTGACTAGCTTTCAAATGGCCAT
CAATACGCAAGATATCAAGGAAATTGAAAAAATATATCAAGAAGTTTTAGTTGATGCAAATTTAAAATTACGCTCGGATA
AATACACTTATTTTGATTTGAACAATGTTGGCGACTCAGCTCTCCGAAGCGTTATGACGGAGACTTTATTCAAGGCGCGT
GAACACCAGATTGATTTGACATTCGAAGTCAAAGATCCTGTTGAGAAATTACCGATTAAGTTATTAGATGTGGTAAGAAT
GGCTAGTATATTGCTAAACAATGCTGTTGAAGGCGCAATCGAAAGCTATGAAAAAATGATTCATGTGACTTTAGTTCAAC
TCGATACGGAAATCATTTTTGTTGTAAAAAATTCCCGCAAGCAAAGGAAATTAGATTTAGAAGAAATTTATGAACCAGAG
TTCTCAACGAAAGGTTATCGAAGAGGACTAGGTTTAAATAATCTGAAAGAAATTTTAGAGAATTATGAATATATCATGCT
AGATACAGAAATAAGTAAGTATGATTTCACCCAAGTATTAACAATTAAAAGAAGGAATAGTTTATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(340-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

55.527

86.83

0.482
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.922

86.161

0.473
  comD Streptococcus mitis NCTC 12261

44

89.286

0.393
  comD/comD1 Streptococcus pneumoniae Rx1

44.444

88.393

0.393
  comD/comD1 Streptococcus pneumoniae D39

44.444

88.393

0.393
  comD/comD1 Streptococcus pneumoniae R6

44.444

88.393

0.393
  comD/comD2 Streptococcus pneumoniae TIGR4

44.974

84.375

0.379
  comD Streptococcus mitis SK321

43.455

85.268

0.371

Multiple sequence alignment