Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Regulator
Locus tag   DQM67_RS10225 Genome accession   NZ_LS483383
Coordinates   1997032..1997160 (-) Length   42 a.a.
NCBI ID   WP_005591382.1    Uniprot ID   O33617
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1992032..2002160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS10595 (NCTC12479_01975) - 1992310..1992969 (+) 660 WP_005591387.1 LysM peptidoglycan-binding domain-containing protein -
  DQM67_RS10195 (NCTC12479_01976) sdaAA 1993025..1993897 (-) 873 WP_005591386.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  DQM67_RS10200 (NCTC12479_01977) sdaAB 1993906..1994577 (-) 672 WP_005592070.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  DQM67_RS10215 (NCTC12479_01980) comE/comE2 1994923..1995666 (-) 744 WP_005591384.1 competence system response regulator transcription factor ComE Regulator
  DQM67_RS10220 (NCTC12479_01981) comD/comD1 1995663..1997009 (-) 1347 WP_376738740.1 sensor histidine kinase Regulator
  DQM67_RS10225 (NCTC12479_01982) comC 1997032..1997160 (-) 129 WP_005591382.1 bacteriocin Regulator
  DQM67_RS10235 (NCTC12479_01984) rlmH 1997455..1997934 (-) 480 WP_005591381.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  DQM67_RS10240 (NCTC12479_01985) htrA 1998137..1999315 (+) 1179 WP_005591380.1 S1C family serine protease Regulator
  DQM67_RS10245 (NCTC12479_01986) spo0J 1999378..2000139 (+) 762 WP_005591379.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 42 a.a.        Molecular weight: 4979.00 Da        Isoelectric Point: 10.9709

>NTDB_id=1139543 DQM67_RS10225 WP_005591382.1 1997032..1997160(-) (comC) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MKNTQKNFKTIAQFPVLNEKELKEVLGGDLRNIFLKIKFKKK

Nucleotide


Download         Length: 129 bp        

>NTDB_id=1139543 DQM67_RS10225 WP_005591382.1 1997032..1997160(-) (comC) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGAAAAATACTCAGAAAAACTTTAAAACAATCGCTCAATTCCCAGTCTTGAATGAAAAAGAACTTAAAGAAGTTCTTGG
AGGAGATTTAAGAAATATCTTCTTAAAAATTAAATTTAAGAAAAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O33617

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus sinensis strain Forsyth1A

63.636

78.571

0.5
  comC Streptococcus mitis SK321

46.154

92.857

0.429

Multiple sequence alignment