Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DQM67_RS07175 Genome accession   NZ_LS483383
Coordinates   1431499..1432200 (-) Length   233 a.a.
NCBI ID   WP_005589489.1    Uniprot ID   A0A3R9LLT9
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1426499..1437200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS07150 (NCTC12479_01386) rnc 1427842..1428531 (-) 690 WP_005589493.1 ribonuclease III -
  DQM67_RS07155 (NCTC12479_01387) - 1428677..1429036 (-) 360 WP_005589492.1 YbaN family protein -
  DQM67_RS07165 (NCTC12479_01388) vicX 1429349..1430149 (-) 801 WP_037586201.1 MBL fold metallo-hydrolase Regulator
  DQM67_RS07170 (NCTC12479_01389) micB 1430142..1431506 (-) 1365 WP_005589490.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM67_RS07175 (NCTC12479_01390) micA 1431499..1432200 (-) 702 WP_005589489.1 response regulator YycF Regulator
  DQM67_RS07180 (NCTC12479_01391) - 1432463..1433545 (+) 1083 WP_005589486.1 Xaa-Pro peptidase family protein -
  DQM67_RS07185 - 1433597..1434104 (-) 508 Protein_1330 methylated-DNA--[protein]-cysteine S-methyltransferase -
  DQM67_RS07190 (NCTC12479_01394) - 1434140..1434997 (-) 858 WP_005589479.1 VOC family protein -
  DQM67_RS07195 (NCTC12479_01395) - 1435227..1435676 (-) 450 WP_005589477.1 Rrf2 family transcriptional regulator -
  DQM67_RS07200 (NCTC12479_01396) - 1435732..1436580 (-) 849 WP_005589476.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26774.74 Da        Isoelectric Point: 4.8934

>NTDB_id=1139514 DQM67_RS07175 WP_005589489.1 1431499..1432200(-) (micA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGKEALEMFEAEQPDILILDLMLPEVDGLDVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKALLRRSELIPDSHVDESSPKELFIGDLQILPDAFVVKKHGKELELTH
REFELLHHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYIRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1139514 DQM67_RS07175 WP_005589489.1 1431499..1432200(-) (micA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGAAAAAAATATTAGTTGTAGATGACGAGAAGCCAATCTCGGACATTATAAAGTTTAACATGGCTAAGGAAGGCTATGA
AGTGCTGACTGCCTTTGATGGTAAGGAAGCTCTAGAAATGTTTGAAGCAGAGCAGCCGGATATCTTGATTCTGGATTTGA
TGTTGCCAGAAGTGGACGGACTGGATGTTGCTCGGACAATCCGTAAGACCAGCAATGTGCCAATCATTGTGCTTTCGGCC
AAAGATAGCGAGTTCGATAAGGTAATTGGTCTGGAAATCGGTGCCGATGACTATGTGACCAAGCCCTTTTCAAATCGTGA
ATTGCTGGCTCGGGTCAAGGCCTTGTTGCGCCGTTCTGAACTAATCCCAGATAGTCACGTGGACGAGAGCAGTCCAAAGG
AACTGTTTATTGGGGATTTGCAGATTCTTCCAGATGCTTTTGTGGTGAAAAAACATGGGAAAGAATTGGAATTAACCCAT
CGTGAATTTGAACTTTTGCACCATTTGGCGACTCATGTTGGTCAAGTCATGACGCGTGAGCACTTGCTGGAAACGGTCTG
GGGCTATGATTACTTTGGAGATGTGCGGACAGTCGATGTAACCATTCGCCGTCTGCGCGAAAAAATCGAAGATACTCCAA
GCCGTCCGGAGTATATCCTGACTCGCCGCGGTGTCGGTTATTACATAAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9LLT9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

100

0.82
  vicR Streptococcus mutans UA159

79.574

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.978

98.283

0.442
  covR Streptococcus salivarius strain HSISS4

42.795

98.283

0.421
  scnR Streptococcus mutans UA159

36.957

98.712

0.365

Multiple sequence alignment