Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   DQM67_RS07170 Genome accession   NZ_LS483383
Coordinates   1430142..1431506 (-) Length   454 a.a.
NCBI ID   WP_005589490.1    Uniprot ID   A0A0F2CQ87
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1425142..1436506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS07150 (NCTC12479_01386) rnc 1427842..1428531 (-) 690 WP_005589493.1 ribonuclease III -
  DQM67_RS07155 (NCTC12479_01387) - 1428677..1429036 (-) 360 WP_005589492.1 YbaN family protein -
  DQM67_RS07165 (NCTC12479_01388) vicX 1429349..1430149 (-) 801 WP_037586201.1 MBL fold metallo-hydrolase Regulator
  DQM67_RS07170 (NCTC12479_01389) micB 1430142..1431506 (-) 1365 WP_005589490.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM67_RS07175 (NCTC12479_01390) micA 1431499..1432200 (-) 702 WP_005589489.1 response regulator YycF Regulator
  DQM67_RS07180 (NCTC12479_01391) - 1432463..1433545 (+) 1083 WP_005589486.1 Xaa-Pro peptidase family protein -
  DQM67_RS07185 - 1433597..1434104 (-) 508 Protein_1330 methylated-DNA--[protein]-cysteine S-methyltransferase -
  DQM67_RS07190 (NCTC12479_01394) - 1434140..1434997 (-) 858 WP_005589479.1 VOC family protein -
  DQM67_RS07195 (NCTC12479_01395) - 1435227..1435676 (-) 450 WP_005589477.1 Rrf2 family transcriptional regulator -

Sequence

Protein


Download         Length: 454 a.a.        Molecular weight: 51573.53 Da        Isoelectric Point: 4.5101

>NTDB_id=1139513 DQM67_RS07170 WP_005589490.1 1430142..1431506(-) (micB) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MIETLKEFVLSPDFVFSLIVVGFIIVVALLLLENRRDTQKLVQLNQKIKGLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDDVLNTSILDLLDIADEYDLRELITKVPE
LTIDSQDENGEYVSLRVRFALIRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALS
EPVAPEFVKVSLTETNRMMRMVTDLLSLSRIDNNTSHLDVELTNFTAFITYILNRFDKIKNQDETKKYEIIRDYSITPIW
VEIDTDKMTQVIDNIMNNAIKYSPDGGTITVSVRTTDVQLILSISDEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHHGFIWAKSEYGKGSTFTIVLPYDNDAVRVDDWENEENVESEHD

Nucleotide


Download         Length: 1365 bp        

>NTDB_id=1139513 DQM67_RS07170 WP_005589490.1 1430142..1431506(-) (micB) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGATTGAAACGCTAAAAGAATTCGTACTTTCTCCTGACTTTGTCTTTTCACTGATTGTTGTCGGCTTTATCATCGTCGT
GGCTCTTTTGCTACTGGAAAATCGACGAGATACTCAAAAGCTGGTGCAGTTAAACCAAAAGATCAAAGGATTGATTGCAG
GAGATTATTCAGAAGTTTTAGATATGCAGGGCAGTCCTGAAATCACGGACATGACCAATTCCATCAATGATCTCTCTGAA
GTCATCCGCCTGACGCATGAAAATTTGGAGCAAGAAACCAAGCGTCTATCCAGTATTTTGTCTTATATGACGGATGGGGT
GCTTGCGACCAATCGTCGAGGGCAGATTATTACCATCAATGACATGGCAACCAAGCAGTTGGGTGTTAAACGTGATGATG
TCCTTAATACCAGTATTTTAGATTTGCTGGATATTGCTGATGAGTACGATCTACGCGAATTGATCACCAAGGTTCCAGAA
TTGACCATTGATTCTCAAGATGAAAATGGTGAATATGTAAGCCTGCGGGTTCGATTTGCCTTGATCAGACGGGAGTCAGG
CTTTATATCAGGGCTGGTAGCAGTGCTGCATGATACAACGGAGCAGGACAAGGAAGAACGGGAGCGTCGGCTTTTCGTTT
CCAATGTTAGCCATGAATTGCGGACGCCTCTAACCAGTGTAAAATCCTATCTGGAAGCCTTGGATGATGGCGCTCTGTCA
GAGCCTGTTGCACCAGAATTTGTCAAGGTTTCACTAACCGAGACAAACCGGATGATGCGGATGGTGACGGACTTGCTTAG
CTTATCGCGGATTGATAATAATACCAGTCATCTGGACGTTGAGCTGACCAATTTTACAGCCTTTATCACCTATATCCTCA
ACCGTTTTGATAAGATAAAAAATCAGGATGAGACCAAAAAATATGAAATTATCAGGGATTATTCAATTACGCCGATTTGG
GTAGAGATTGATACGGATAAGATGACCCAGGTGATTGATAATATCATGAACAATGCCATCAAGTATTCACCTGATGGTGG
GACGATTACGGTTTCTGTGAGAACAACAGATGTTCAGTTGATTCTCTCGATTTCAGATGAAGGTCTGGGCATTCCCAAAC
AGGATCTGCCAAAGATTTTTGATCGTTTCTATCGGGTGGATAAGGCCCGTAGTCGAGCCCAGGGAGGAACGGGCTTGGGT
CTGGCTATTGCTAAAGAAATTATCAAGCAGCATCATGGCTTTATCTGGGCTAAGAGTGAGTATGGCAAAGGCTCTACCTT
TACCATTGTCCTTCCATATGATAACGATGCTGTCCGTGTAGATGACTGGGAAAATGAAGAGAATGTAGAAAGTGAACATG
ACTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2CQ87

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

78.588

96.696

0.76
  vicK Streptococcus mutans UA159

71.642

88.546

0.634

Multiple sequence alignment