Detailed information NTG1139511

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: DQM67_RS07115
• Genome accession: NZ_LS483383
• Coordinates: 1419656..1420246 (-)
• Length: 196 a.a.
• NCBI ID: WP_005592197.1
• Uniprot ID: A0A139MYQ9
• Organism: Streptococcus cristatus ATCC 51100 strain NCTC 12479
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1414656..1425246

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM67_RS07090 (NCTC12479_01375)	-	1415298..1416062 (-)	765	WP_005589509.1	ABC transporter ATP-binding protein	-
DQM67_RS07095 (NCTC12479_01376)	-	1416062..1417015 (-)	954	WP_005589507.1	branched-chain amino acid ABC transporter permease	-
DQM67_RS07100 (NCTC12479_01377)	-	1417019..1417900 (-)	882	WP_005589506.1	branched-chain amino acid ABC transporter permease	-
DQM67_RS07105 (NCTC12479_01378)	-	1418040..1419200 (-)	1161	WP_005589505.1	ABC transporter substrate-binding protein	-
DQM67_RS07110 (NCTC12479_01379)	-	1419300..1419569 (-)	270	WP_005589504.1	DUF2129 domain-containing protein	-
DQM67_RS07115 (NCTC12479_01380)	clpP	1419656..1420246 (-)	591	WP_005592197.1	ATP-dependent Clp protease proteolytic subunit	Regulator
DQM67_RS07120 (NCTC12479_01381)	upp	1420418..1421047 (-)	630	WP_015605186.1	uracil phosphoribosyltransferase	-
DQM67_RS07130 (NCTC12479_01382)	ftsY	1421192..1422688 (-)	1497	WP_005589501.1	signal recognition particle-docking protein FtsY	-
DQM67_RS07135 (NCTC12479_01383)	-	1422692..1423510 (-)	819	WP_005589500.1	Cof-type HAD-IIB family hydrolase	-
DQM67_RS07140 (NCTC12479_01384)	-	1423510..1424304 (-)	795	WP_005589497.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21447.43 Da
• Isoelectric Point: 4.4829

>NTDB_id=1139511 DQM67_RS07115 WP_005592197.1 1419656..1420246(-) (clpP) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRRTLEQILADNSGK
SVEQIHADAERDYWMSAQETLEYGFIDEIMANNNLS

Nucleotide

• Length: 591 bp

>NTDB_id=1139511 DQM67_RS07115 WP_005592197.1 1419656..1420246(-) (clpP) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGATTCCTGTAGTTATTGAACAAACCAGCCGTGGTGAGCGTTCTTATGACATTTACTCACGCCTTTTAAAAGACCGTAT
TATCATGCTGACGGGTCCTGTTGAGGACAATATGGCTAATTCTGTTATTGCGCAACTGCTTTTCCTAGATGCACAAGACA
GCACCAAGGACATCTATCTTTATGTTAATACTCCTGGTGGCTCTGTGTCAGCGGGATTGGCGATTGTAGATACCATGAAC
TTTATTAAGTCTGATGTGCAGACGATTGTCATGGGAATGGCAGCTAGCATGGGAACTATCATTGCTTCTAGCGGTGCTAA
GGGCAAACGATTCATGCTTCCAAATGCAGAGTATATGATTCACCAGCCGATGGGTGGTACTGGTGGCGGTACTCAGCAAA
CAGATATGGCCATTGCAGCAGAGCATTTGCTTAAGACTCGTAGGACCTTGGAGCAAATTCTTGCCGACAATTCTGGTAAA
TCGGTTGAGCAGATTCACGCAGATGCAGAACGTGATTACTGGATGAGTGCCCAAGAAACCTTGGAATATGGTTTTATCGA
TGAAATCATGGCTAATAATAATCTTAGCTAG

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A139MYQ9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	93.878	100	0.939
clpP	Streptococcus pneumoniae D39	93.878	100	0.939
clpP	Streptococcus pneumoniae R6	93.878	100	0.939
clpP	Streptococcus pneumoniae TIGR4	93.878	100	0.939
clpP	Streptococcus thermophilus LMD-9	92.308	99.49	0.918
clpP	Streptococcus thermophilus LMG 18311	92.308	99.49	0.918
clpP	Streptococcus pyogenes MGAS315	90.816	100	0.908
clpP	Streptococcus pyogenes JRS4	90.816	100	0.908
clpP	Streptococcus mutans UA159	89.231	99.49	0.888
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.692	99.49	0.872
clpP	Lactococcus lactis subsp. cremoris KW2	87.179	99.49	0.867
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571
clpP	Bacillus subtilis subsp. subtilis str. 168	57.292	97.959	0.561