Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM89_RS01495 Genome accession   NZ_LS483382
Coordinates   275083..275634 (+) Length   183 a.a.
NCBI ID   WP_111721343.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC13738     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 270083..280634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM89_RS01495 (NCTC13738_00296) comX/sigX/comX2/sigX2 275083..275634 (+) 552 WP_111721343.1 sigma-70 family RNA polymerase sigma factor Regulator
  DQM89_RS01500 (NCTC13738_00297) - 276215..276742 (+) 528 WP_002991099.1 YqeG family HAD IIIA-type phosphatase -
  DQM89_RS01505 (NCTC13738_00298) yqeH 276742..277860 (+) 1119 WP_023078962.1 ribosome biogenesis GTPase YqeH -
  DQM89_RS01510 (NCTC13738_00299) yhbY 277885..278193 (+) 309 WP_002991094.1 ribosome assembly RNA-binding protein YhbY -
  DQM89_RS01515 (NCTC13738_00300) - 278262..278894 (+) 633 WP_011184179.1 nicotinate-nucleotide adenylyltransferase -
  DQM89_RS01520 (NCTC13738_00301) yqeK 278891..279484 (+) 594 WP_002985989.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DQM89_RS01525 (NCTC13738_00302) rsfS 279508..279861 (+) 354 WP_015055915.1 ribosome silencing factor -

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22181.00 Da        Isoelectric Point: 10.1136

>NTDB_id=1139442 DQM89_RS01495 WP_111721343.1 275083..275634(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC13738]
MSCCFFVVLFILGIVKKKRRLKMSIGTRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIKGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=1139442 DQM89_RS01495 WP_111721343.1 275083..275634(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC13738]
GTGTCCTGTTGCTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGGGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAAGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.361

100

0.984
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.361

100

0.984
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.361

100

0.984
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.361

100

0.984
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

45.455

84.153

0.383
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment