Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQM75_RS06935 Genome accession   NZ_LS483380
Coordinates   1462952..1463662 (-) Length   236 a.a.
NCBI ID   WP_012515994.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11824     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1457952..1468662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM75_RS06920 (NCTC11824_01393) - 1458376..1459890 (-) 1515 WP_231199561.1 helix-turn-helix domain-containing protein -
  DQM75_RS06925 (NCTC11824_01394) vicX 1460794..1461603 (-) 810 WP_111692627.1 MBL fold metallo-hydrolase Regulator
  DQM75_RS06930 (NCTC11824_01395) vicK 1461607..1462959 (-) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM75_RS06935 (NCTC11824_01396) vicR 1462952..1463662 (-) 711 WP_012515994.1 response regulator YycF Regulator
  DQM75_RS06940 (NCTC11824_01397) - 1463869..1464888 (-) 1020 WP_111692929.1 DUF3114 domain-containing protein -
  DQM75_RS06945 (NCTC11824_01398) - 1464934..1466196 (-) 1263 WP_111692628.1 AMP-binding protein -
  DQM75_RS06950 (NCTC11824_01399) - 1466186..1467301 (-) 1116 WP_042670956.1 acetyl-CoA C-acyltransferase -
  DQM75_RS06955 (NCTC11824_01400) - 1467298..1467837 (-) 540 WP_111692629.1 hypothetical protein -
  DQM75_RS06960 - 1467969..1468118 (-) 150 Protein_1343 aquaporin family protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26981.84 Da        Isoelectric Point: 4.9038

>NTDB_id=1139344 DQM75_RS06935 WP_012515994.1 1462952..1463662(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1139344 DQM75_RS06935 WP_012515994.1 1462952..1463662(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGAAGAAAATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGCTATGA
TACGGTCACAGCATTTGATGGCAAAGAGGCCGTTGCAGTCTTTGAAGAGGAAAAGCCAGATTTGATTATTTTGGATTTGA
TGCTTCCTGAATTAGATGGCCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGACTTGAAATAGGGGCTGATGATTATGTGACTAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCTGAAGAAAATGCCTCCTCAG
GCTCTCAGGAGCTGACCATCGGCAATCTACAGATTTTACCAGATGCCTTTATCGCTAAAAAGCATGGTCAAGAGGTTGAG
CTGACCCATCGTGAGTTTGAATTGCTTCATCACCTAGCAAACCATATCGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACTGTATGGGGCTACGATTATTTTGGCGATGTCCGAACCGTTGACGTTACTATCCGTCGCCTGCGCGAAAAAATAGAGG
ATACACCGAGTCGTCCGGAGTACATCTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.983

100

0.89
  micA Streptococcus pneumoniae Cp1015

78.112

98.729

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.034

99.153

0.377

Multiple sequence alignment