Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DQM75_RS06930 Genome accession   NZ_LS483380
Coordinates   1461607..1462959 (-) Length   450 a.a.
NCBI ID   WP_014623188.1    Uniprot ID   A0A6M1KZW6
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11824     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1456607..1467959
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM75_RS06915 (NCTC11824_01392) rnc 1457426..1458118 (-) 693 WP_038674782.1 ribonuclease III -
  DQM75_RS06920 (NCTC11824_01393) - 1458376..1459890 (-) 1515 WP_231199561.1 helix-turn-helix domain-containing protein -
  DQM75_RS06925 (NCTC11824_01394) vicX 1460794..1461603 (-) 810 WP_111692627.1 MBL fold metallo-hydrolase Regulator
  DQM75_RS06930 (NCTC11824_01395) vicK 1461607..1462959 (-) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM75_RS06935 (NCTC11824_01396) vicR 1462952..1463662 (-) 711 WP_012515994.1 response regulator YycF Regulator
  DQM75_RS06940 (NCTC11824_01397) - 1463869..1464888 (-) 1020 WP_111692929.1 DUF3114 domain-containing protein -
  DQM75_RS06945 (NCTC11824_01398) - 1464934..1466196 (-) 1263 WP_111692628.1 AMP-binding protein -
  DQM75_RS06950 (NCTC11824_01399) - 1466186..1467301 (-) 1116 WP_042670956.1 acetyl-CoA C-acyltransferase -
  DQM75_RS06955 (NCTC11824_01400) - 1467298..1467837 (-) 540 WP_111692629.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51527.91 Da        Isoelectric Point: 5.5557

>NTDB_id=1139343 DQM75_RS06930 WP_014623188.1 1461607..1462959(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1139343 DQM75_RS06930 WP_014623188.1 1461607..1462959(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCACAAGATAAGAGATTTGATCAATG
GTCGCTATACAGACACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAATGACCTATCAGAT
GTTTTTCGTCTGACTCATGAAAACCTTGCTCAAGAAAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGCGAGCAGG
CCTTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCCCCTTATACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAACCGTCGTAATGATACAGGAGAATTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAAAGCGG
CTTTATTTCAGGTCTGGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAAGAGCGCGAGCGCAGACTCTTTGTTT
CAAATGTTAGCCATGAGCTGCGGACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATCGCTCCAAGCTTTATAAAGGTCTCACTAGATGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
CCTCTCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATTACCTCT
ATTTGGCTAGAAATTGACAATGACAAAATGACGCAGGTTATCGAAAATATTTTAAACAATGCGATCAAATATTCACCCGA
TGGCGGAAAAATTGTCGTCAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGCTTGGGCATAC
CAAAGAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGGAGTAGAGCTCAAGGAGGAACTGGT
CTAGGCTTAGCGATTGCTAAAGAAATTATTAAGCAGCACCGCGGCTTTATCTGGGCTAAGAGTGACTATGGCAAGGGGTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M1KZW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631

Multiple sequence alignment