Detailed information NTG0113923

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: Q426_RS08535
• Genome accession: NZ_CP006770
• Coordinates: 1820989..1821903 (-)
• Length: 304 a.a.
• NCBI ID: WP_014622102.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus CY
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1815989..1826903

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q426_RS08515 (Q426_09120)	-	1816882..1818663 (-)	1782	WP_014622105.1	acyltransferase family protein	-
Q426_RS08520 (Q426_09125)	-	1818660..1819061 (-)	402	WP_012514718.1	MORN repeat-containing protein	-
Q426_RS08525 (Q426_09130)	-	1819067..1819525 (-)	459	WP_012514717.1	low molecular weight protein-tyrosine-phosphatase	-
Q426_RS08530 (Q426_09135)	ruvB	1819773..1820774 (-)	1002	WP_014622103.1	Holliday junction branch migration DNA helicase RuvB	-
Q426_RS10705 (Q426_09140)	comS	1820808..1820906 (-)	99	WP_200831644.1	quorum-sensing system DWW-type pheromone	Regulator
Q426_RS08535 (Q426_09145)	comR	1820989..1821903 (-)	915	WP_014622102.1	helix-turn-helix domain-containing protein	Regulator
Q426_RS08540 (Q426_09150)	purB	1822202..1823494 (-)	1293	WP_038674659.1	adenylosuccinate lyase	-
Q426_RS08545 (Q426_09160)	-	1824087..1824311 (-)	225	WP_014622100.1	hypothetical protein	-
Q426_RS08550 (Q426_09165)	purK	1824326..1825399 (-)	1074	WP_014622099.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
Q426_RS08555 (Q426_09170)	purE	1825386..1825874 (-)	489	WP_014622098.1	5-(carboxyamino)imidazole ribonucleotide mutase	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35851.29 Da
• Isoelectric Point: 4.4139

>NTDB_id=113923 Q426_RS08535 WP_014622102.1 1820989..1821903(-) (comR) [Streptococcus equi subsp. zooepidemicus CY]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDVEMAEKCYDKACLFAQLTGDQYLEKKLREEWDKDIKQYQ

Nucleotide

• Length: 915 bp

>NTDB_id=113923 Q426_RS08535 WP_014622102.1 1820989..1821903(-) (comR) [Streptococcus equi subsp. zooepidemicus CY]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTATATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGACGATGACAAATTAAAGCTACGTGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGATCAGCTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCGATAATGGATACGTTATTAACTG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATTCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTTTAATGAAGAAAAAAGACGTAGA
AATGGCAGAAAAATGTTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTAGAAAAGAAATTAAGAG
AAGAATGGGATAAAGATATAAAACAATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.257	99.671	0.74
comR	Streptococcus pyogenes MGAS315	54.153	99.013	0.536
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	49.164	98.355	0.484
comR	Streptococcus suis D9	38.206	99.013	0.378
comR	Streptococcus suis 05ZYH33	38.983	97.039	0.378
comR	Streptococcus suis P1/7	38.983	97.039	0.378