Detailed information NTG1139200

Bioinformatically predicted

Overview

• Name: comR/comR1
• Type: Regulator
• Locus tag: DQM97_RS00270
• Genome accession: NZ_LS483378
• Coordinates: 39855..40760 (+)
• Length: 301 a.a.
• NCBI ID: WP_002959603.1
• Uniprot ID: -
• Organism: Streptococcus sobrinus strain NCTC12279
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 34855..45760

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM97_RS00240 (NCTC12279_00047)	-	34890..35024 (+)	135	WP_021674295.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DQM97_RS10995 (NCTC12279_00048)	-	35054..35182 (+)	129	WP_019768929.1	hypothetical protein	-
DQM97_RS10755 (NCTC12279_00049)	-	35237..35380 (+)	144	WP_002959617.1	hypothetical protein	-
DQM97_RS00245 (NCTC12279_00050)	-	35642..36463 (+)	822	WP_019768928.1	ABC transporter ATP-binding protein	-
DQM97_RS00250 (NCTC12279_00051)	-	36453..37172 (+)	720	WP_002959613.1	ABC transporter permease	-
DQM97_RS11000 (NCTC12279_00053)	-	37414..37542 (+)	129	WP_019768926.1	hypothetical protein	-
DQM97_RS00255	-	37673..37903 (+)	231	WP_002959611.1	hypothetical protein	-
DQM97_RS00260 (NCTC12279_00054)	-	38167..39504 (+)	1338	WP_028798494.1	lipase	-
DQM97_RS00265 (NCTC12279_00055)	-	39530..39688 (+)	159	WP_002959605.1	bacteriocin	-
DQM97_RS00270 (NCTC12279_00056)	comR/comR1	39855..40760 (+)	906	WP_002959603.1	helix-turn-helix domain-containing protein	Regulator
DQM97_RS00275 (NCTC12279_00057)	comA	41020..43137 (+)	2118	WP_002959601.1	peptide cleavage/export ABC transporter	Regulator
DQM97_RS00280	-	43331..44233 (+)	903	Protein_36	helix-turn-helix domain-containing protein	-
DQM97_RS00285 (NCTC12279_00060)	-	44363..45235 (-)	873	WP_002959599.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 301 a.a.
• Molecular weight: 35500.52 Da
• Isoelectric Point: 4.3817

>NTDB_id=1139200 DQM97_RS00270 WP_002959603.1 39855..40760(+) (comR/comR1) [Streptococcus sobrinus strain NCTC12279]
MTIKADLGRRIKAERNQKKISQSSFCGDEEKLTIRQLQRIEHGQSLPTLEKLEFIADRLDIKMSDLLEGRDIQLPDDYWE
MKARIVKFPTYGDEERIQQKQNLIDEIYDKYFDSLPEDELLFLDLSENILGGIHDKNIPDIEEIYDDAFDQVLKKERFDF
NDYLYLGYFLQQCRKDSDYDYKTFKKIEQKLLKQELLADDLYNIELLATVMDAATVYAFHDDYGNIMPLLEKLNRIIEKA
QLPTYKVGLLELEAKYYIKVVEDKEKAKELYQRALMLGDILDDPTIIADVKMEMKNDGIDE

Nucleotide

• Length: 906 bp

>NTDB_id=1139200 DQM97_RS00270 WP_002959603.1 39855..40760(+) (comR/comR1) [Streptococcus sobrinus strain NCTC12279]
ATGACAATAAAAGCAGATTTAGGACGACGGATTAAGGCCGAAAGAAACCAGAAAAAAATATCGCAGAGTTCATTTTGCGG
GGACGAAGAAAAGCTAACGATTCGTCAGTTGCAGCGGATTGAGCATGGCCAATCCCTACCAACTCTAGAAAAGTTGGAAT
TTATCGCTGATCGTTTGGACATTAAAATGTCTGACCTTCTGGAAGGTAGGGATATCCAATTACCGGATGACTATTGGGAA
ATGAAAGCACGGATTGTTAAATTTCCTACCTATGGAGATGAGGAAAGAATCCAGCAAAAACAGAATCTCATTGATGAAAT
TTATGATAAATACTTTGACAGTCTACCTGAGGATGAACTGCTCTTTTTGGACCTTTCAGAAAATATTCTAGGGGGTATTC
ATGACAAGAATATTCCTGATATTGAAGAAATTTATGATGATGCCTTCGATCAGGTTCTTAAAAAGGAGAGGTTTGATTTT
AACGATTACCTTTATTTGGGCTATTTTTTGCAACAGTGTCGCAAGGATTCCGATTATGATTATAAGACTTTTAAAAAAAT
TGAGCAGAAATTACTAAAGCAGGAGCTATTGGCAGATGATCTCTATAATATTGAACTTTTAGCGACAGTAATGGATGCTG
CTACTGTCTATGCTTTTCATGATGATTATGGAAATATCATGCCCTTGTTAGAAAAGCTGAATCGTATTATTGAGAAAGCT
CAACTCCCCACCTACAAGGTAGGACTTTTAGAACTTGAGGCCAAGTACTATATTAAGGTTGTTGAAGATAAAGAAAAAGC
CAAAGAACTTTACCAGCGCGCTCTGATGCTGGGAGATATTCTAGATGATCCCACCATTATTGCTGATGTTAAGATGGAAA
TGAAAAATGATGGGATAGATGAATAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	98.671	100	0.987
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	72.333	99.668	0.721
comR	Streptococcus thermophilus LMG 18311	41.806	99.336	0.415
comR	Streptococcus salivarius strain HSISS4	41.806	99.336	0.415
comR	Streptococcus thermophilus LMD-9	41.137	99.336	0.409
comR	Streptococcus salivarius SK126	41.137	99.336	0.409