Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   DQM97_RS00275 Genome accession   NZ_LS483378
Coordinates   41020..43137 (+) Length   705 a.a.
NCBI ID   WP_002959601.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC12279     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 36020..48137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM97_RS00250 (NCTC12279_00051) - 36453..37172 (+) 720 WP_002959613.1 ABC transporter permease -
  DQM97_RS11000 (NCTC12279_00053) - 37414..37542 (+) 129 WP_019768926.1 hypothetical protein -
  DQM97_RS00255 - 37673..37903 (+) 231 WP_002959611.1 hypothetical protein -
  DQM97_RS00260 (NCTC12279_00054) - 38167..39504 (+) 1338 WP_028798494.1 lipase -
  DQM97_RS00265 (NCTC12279_00055) - 39530..39688 (+) 159 WP_002959605.1 bacteriocin -
  DQM97_RS00270 (NCTC12279_00056) comR/comR1 39855..40760 (+) 906 WP_002959603.1 helix-turn-helix domain-containing protein Regulator
  DQM97_RS00275 (NCTC12279_00057) comA 41020..43137 (+) 2118 WP_002959601.1 peptide cleavage/export ABC transporter Regulator
  DQM97_RS00280 - 43331..44233 (+) 903 Protein_36 helix-turn-helix domain-containing protein -
  DQM97_RS00285 (NCTC12279_00060) - 44363..45235 (-) 873 WP_002959599.1 helix-turn-helix domain-containing protein -
  DQM97_RS00290 (NCTC12279_00061) - 45554..46312 (+) 759 WP_002959597.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 705 a.a.        Molecular weight: 78964.55 Da        Isoelectric Point: 8.9748

>NTDB_id=1139201 DQM97_RS00275 WP_002959601.1 41020..43137(+) (comA) [Streptococcus sobrinus strain NCTC12279]
MKKYTYIAQVDERDCGVAALAMVLKHYGSTYSLAYLRELAQTSREGTSALGLIRAAQGLGLKTKAIRAQLDLFDDEHLTY
PFIVHVVKDESLQHYYTVFGQDGDKIIIGDPDPGKKVVKLPRSQFEKEWTGVALFFEPSETYTVHKEKLKGLWSFVPILL
KKKTLIAVIVAMSFMVTVINIVGSYYLQGMLDSLIPRAMYSFLTIVSLGLCLAYLAQQVFQFFQTYLLSRLSNYLAAQVI
LPYIKHVLSLPMSFFTSRRTGEITSRFGDASTIIDALASTILSLFLDLTIVITLAVTLFVQSTQLFSLTLLVVPLYALVI
LSFLKFFDHQNYQVMEANSKVNTAIIDDLRGIETLKSLRVEKRRYSSIEGKFSDYLTKSLKRSQWEAIQTSLKTIVQLVF
NVLILWYGANLVMRGQLSIGQLITYNMLLTYFTTPLTNIINLQGKLQQARVANNRLQEVYVVDKEEEAKNDVKDFTSLQL
SGVGHRFSYQQETLKDIDLSIERGDKIALMGKSGSGKTTLAKILAGYYTVNQGKTLIDERSVGYPELRSLVTYVPQQSYV
FTGTILENLLLGVSGDVDEKRLIEACTTAEILEDIQAMPLGFQSQVSEDGGLSGGQKQRLAIARALLSDQPILVFDEATS
GLDGDTEEKVIKNLNSIDRTMIFVAHRGSISNYANRIVKIEAGKKISDQPNQKLRWSRLGLGHVV

Nucleotide


Download         Length: 2118 bp        

>NTDB_id=1139201 DQM97_RS00275 WP_002959601.1 41020..43137(+) (comA) [Streptococcus sobrinus strain NCTC12279]
TTGAAAAAGTATACCTATATTGCCCAGGTAGATGAGCGCGATTGTGGGGTAGCGGCCTTGGCCATGGTCCTTAAGCATTA
TGGATCGACCTATAGTTTGGCCTACCTTAGGGAACTGGCTCAGACCTCTCGGGAAGGAACCTCTGCCTTGGGCTTGATAA
GGGCGGCCCAAGGTTTAGGACTTAAAACCAAGGCTATCCGAGCGCAATTAGATCTTTTTGATGATGAGCATTTGACCTAT
CCCTTTATCGTTCATGTTGTTAAGGATGAGAGTCTGCAACACTACTACACGGTCTTTGGGCAAGATGGAGATAAGATTAT
TATCGGCGATCCTGATCCTGGGAAGAAGGTTGTTAAGTTGCCACGTTCGCAATTTGAAAAAGAATGGACAGGTGTTGCTC
TTTTCTTTGAACCGAGCGAGACTTATACAGTTCACAAGGAGAAGCTCAAAGGGCTCTGGTCTTTTGTACCAATCTTACTG
AAAAAGAAGACCTTGATTGCCGTTATTGTTGCCATGAGTTTTATGGTGACCGTAATTAATATCGTTGGGTCATACTATTT
GCAAGGGATGTTGGATAGCTTGATTCCAAGAGCCATGTACTCATTTTTGACGATTGTCTCCTTAGGGCTCTGTCTTGCTT
ATCTGGCTCAACAGGTCTTCCAATTTTTCCAGACCTACTTGCTCTCTCGTCTCAGCAATTATCTAGCTGCACAGGTCATC
CTTCCTTATATTAAGCATGTCCTGTCTCTGCCGATGAGCTTCTTTACCTCTCGGCGGACTGGTGAGATTACTTCACGTTT
TGGCGATGCTAGCACAATTATTGATGCCTTAGCTTCAACGATTTTGTCACTCTTCTTGGATTTGACGATTGTTATTACCT
TGGCTGTGACCCTCTTTGTACAAAGTACACAGCTCTTTAGTTTGACTTTACTGGTGGTTCCTCTCTATGCCTTGGTGATT
CTATCCTTCCTCAAATTTTTTGATCATCAGAACTATCAGGTAATGGAAGCTAATAGTAAGGTTAACACCGCTATCATTGA
TGATTTGCGGGGGATTGAAACGCTTAAATCCCTACGAGTTGAAAAGCGGCGTTACTCTTCAATTGAAGGTAAGTTCTCAG
ATTATTTGACTAAGTCTCTGAAGCGGAGTCAGTGGGAGGCTATTCAAACGAGCTTGAAGACGATTGTCCAGCTTGTCTTT
AATGTCTTGATTCTTTGGTATGGGGCTAATTTGGTGATGCGTGGTCAACTCTCAATAGGGCAGTTGATTACCTATAACAT
GCTGCTGACTTATTTTACAACCCCCCTGACCAATATTATTAATTTGCAAGGAAAACTCCAACAAGCGCGTGTTGCTAACA
ACCGCCTCCAAGAAGTATATGTGGTTGATAAGGAAGAAGAGGCTAAAAATGATGTGAAAGACTTTACCAGCCTTCAGCTA
TCGGGTGTGGGCCATCGCTTTAGCTACCAACAAGAAACCTTAAAGGATATTGACTTATCAATTGAGCGCGGTGATAAGAT
TGCCCTGATGGGTAAGAGTGGTTCTGGTAAGACAACTTTGGCTAAGATTTTAGCGGGTTACTATACTGTAAACCAAGGTA
AAACTCTGATTGATGAGCGGTCTGTTGGTTATCCTGAATTGAGGAGTTTGGTTACCTATGTTCCCCAACAATCCTATGTG
TTCACAGGAACCATTTTGGAAAACCTCCTGCTTGGAGTGTCCGGTGATGTTGATGAGAAACGTTTGATAGAAGCTTGTAC
TACAGCTGAAATTTTAGAAGATATTCAAGCTATGCCGCTAGGCTTTCAATCTCAAGTTTCCGAAGATGGTGGCCTGTCGG
GTGGGCAAAAGCAACGGTTAGCCATTGCTCGGGCTCTGCTTTCAGACCAGCCAATTTTAGTCTTTGACGAAGCCACAAGT
GGACTTGATGGTGATACGGAAGAAAAAGTTATTAAAAATCTCAATAGTATCGATCGGACCATGATTTTTGTTGCCCACCG
AGGTAGCATCTCAAATTATGCTAACCGAATTGTTAAGATTGAGGCTGGTAAAAAAATTAGCGATCAACCCAACCAAAAAC
TCAGGTGGTCACGTTTAGGTTTAGGCCATGTTGTTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-140)

ABC transporter transmembrane region (ABC_membrane)

(168-436)

ABC transporter (ABC_tran)

(494-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

51.286

99.291

0.509
  comA Streptococcus pneumoniae D39

51.286

99.291

0.509
  comA Streptococcus pneumoniae R6

51.286

99.291

0.509
  comA Streptococcus pneumoniae Rx1

51.286

99.291

0.509
  comA Streptococcus gordonii str. Challis substr. CH1

50.563

100

0.509
  comA Streptococcus pneumoniae TIGR4

51.143

99.291

0.508
  comA Streptococcus mitis NCTC 12261

51.297

98.44

0.505
  comA/nlmT Streptococcus mutans UA159

49.358

99.433

0.491

Multiple sequence alignment