Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DQM54_RS03840 Genome accession   NZ_LS483375
Coordinates   776375..777076 (+) Length   233 a.a.
NCBI ID   WP_008809004.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC3165     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 771375..782076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM54_RS03810 (NCTC3165_00754) - 772001..772363 (+) 363 WP_111723478.1 hypothetical protein -
  DQM54_RS10920 (NCTC3165_00756) - 772697..773068 (+) 372 WP_111724283.1 hypothetical protein -
  DQM54_RS03825 (NCTC3165_00757) thrS 773160..775103 (+) 1944 WP_111723479.1 threonine--tRNA ligase -
  DQM54_RS03830 (NCTC3165_00758) - 775158..775520 (-) 363 WP_111723480.1 MerR family transcriptional regulator -
  DQM54_RS03835 (NCTC3165_00759) - 775598..775975 (+) 378 WP_002899930.1 carboxymuconolactone decarboxylase family protein -
  DQM54_RS03840 (NCTC3165_00760) micA 776375..777076 (+) 702 WP_008809004.1 response regulator YycF Regulator
  DQM54_RS03845 (NCTC3165_00761) micB 777069..778430 (+) 1362 WP_111723481.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM54_RS03850 (NCTC3165_00762) vicX 778423..779226 (+) 804 WP_045634630.1 MBL fold metallo-hydrolase Regulator
  DQM54_RS03855 (NCTC3165_00763) - 779261..779617 (+) 357 WP_008809001.1 YbaN family protein -
  DQM54_RS03860 (NCTC3165_00764) rnc 779860..780558 (+) 699 WP_061601751.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26790.54 Da        Isoelectric Point: 4.6297

>NTDB_id=1139114 DQM54_RS03840 WP_008809004.1 776375..777076(+) (micA) [Streptococcus gordonii strain NCTC3165]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAENPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKAILRRSEFAVDTQESEKGSNELTVGELQILPDAFVAKKHGEELELTH
REFELLYHLASHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1139114 DQM54_RS03840 WP_008809004.1 776375..777076(+) (micA) [Streptococcus gordonii strain NCTC3165]
ATGAAGAAAATATTAGTTGTAGATGATGAAAAACCAATTTCAGATATTATAAAATTTAATATGGTAAAAGAGGGCTATGA
AGTTGTTACGGCTTTTGATGGTCGTGAAGCTCTTGAGATGTTTGAAGCTGAAAATCCTGATATTTTGATTTTGGATTTGA
TGTTGCCAGAGTTGGACGGGCTAGAAGTAGCACGCACCATTCGGAAGACCAGTAATGTTCCAATTATTGTCCTATCGGCT
AAAGATAGTGAGTTTGATAAAGTTATCGGCCTTGAGATCGGAGCAGACGACTATGTGACCAAGCCTTTCTCTAACCGTGA
GCTCCAAGCTCGTGTCAAGGCTATTTTGCGACGTTCAGAATTTGCTGTAGATACCCAAGAAAGTGAAAAGGGCTCAAATG
AGTTGACAGTGGGTGAATTGCAAATTTTACCCGATGCTTTTGTTGCCAAGAAACATGGTGAAGAGCTAGAATTAACCCAT
CGTGAGTTTGAATTACTCTACCATTTGGCTAGTCATGTTGGTCAAGTAATGACACGCGAACACCTACTAGAGACAGTTTG
GGGTTATGATTATTTTGGTGATGTACGCACTGTTGATGTGACGATTCGCCGTCTACGTGAAAAGATTGAAGATACGCCAA
GCCGACCAGAGTATATTTTAACTCGTCGTGGTGTTGGCTATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.12

100

0.841
  vicR Streptococcus mutans UA159

79.574

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  covR Streptococcus salivarius strain HSISS4

44.105

98.283

0.433
  scnR Streptococcus mutans UA159

37.5

99.571

0.373

Multiple sequence alignment