Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQM56_RS07045 Genome accession   NZ_LS483368
Coordinates   1466742..1467452 (-) Length   236 a.a.
NCBI ID   WP_012677635.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6176     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1461742..1472452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM56_RS07030 (NCTC6176_01426) - 1462168..1463682 (-) 1515 WP_014623184.1 helix-turn-helix domain-containing protein -
  DQM56_RS07035 (NCTC6176_01427) vicX 1464584..1465393 (-) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  DQM56_RS07040 (NCTC6176_01428) vicK 1465397..1466749 (-) 1353 WP_111710693.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM56_RS07045 (NCTC6176_01429) vicR 1466742..1467452 (-) 711 WP_012677635.1 response regulator YycF Regulator
  DQM56_RS07050 (NCTC6176_01430) - 1467638..1468669 (-) 1032 WP_111710942.1 DUF3114 domain-containing protein -
  DQM56_RS07055 (NCTC6176_01431) - 1468715..1469977 (-) 1263 WP_111710694.1 AMP-binding protein -
  DQM56_RS07060 (NCTC6176_01432) - 1469967..1471082 (-) 1116 WP_111710695.1 acetyl-CoA C-acyltransferase -
  DQM56_RS07065 (NCTC6176_01433) - 1471079..1471618 (-) 540 WP_111710696.1 hypothetical protein -
  DQM56_RS07070 - 1471750..1471899 (-) 150 Protein_1355 aquaporin family protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26967.81 Da        Isoelectric Point: 4.9038

>NTDB_id=1138906 DQM56_RS07045 WP_012677635.1 1466742..1467452(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1138906 DQM56_RS07045 WP_012677635.1 1466742..1467452(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGAAGAAGATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGTTATGA
TACGGTTACAGCCTTTGATGGCAAAGAAGCCGTTGCAGTCTTTGAAGAGGAAAAGCCGGATTTGATTATTTTGGATTTGA
TGCTTCCTGAGCTAGATGGCCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGCCTTGAAATAGGGGCCGATGATTATGTGACCAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCCGAAGAAAATGCTTCTTCAG
GCTCTCAGGAGCTGACCATCGGCAATCTACAGATTTTGCCAGATGCCTTTATCGCTAAAAAGCATGGTCAAGAGGTTGAG
CTGACCCATCGTGAATTTGAATTGCTGCATCACCTGGCAAACCATATTGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACCGTATGGGGCTATGATTATTTTGGCGATGTCCGAACCGTTGACGTTACTGTCCGTCGCCTGCGTGAAAAAATAGAGG
ACACACCGAGTCGTCCGGAGTACATCTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

89.407

100

0.894
  micA Streptococcus pneumoniae Cp1015

78.541

98.729

0.775
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  covR Streptococcus salivarius strain HSISS4

43.966

98.305

0.432
  scnR Streptococcus mutans UA159

37.607

99.153

0.373

Multiple sequence alignment