Detailed information NTG1138803

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQM60_RS09565
• Genome accession: NZ_LS483366
• Coordinates: 2036256..2036693 (-)
• Length: 145 a.a.
• NCBI ID: WP_037601472.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain NCTC7366
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2031256..2041693

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM60_RS09530 (NCTC7366_01930)	-	2031295..2031957 (-)	663	WP_111686674.1	CPBP family intramembrane glutamic endopeptidase	-
DQM60_RS09535 (NCTC7366_01931)	-	2032070..2032516 (-)	447	WP_013991259.1	hypothetical protein	-
DQM60_RS09540 (NCTC7366_01932)	-	2032594..2033250 (-)	657	WP_037601483.1	CPBP family intramembrane glutamic endopeptidase	-
DQM60_RS09545 (NCTC7366_01933)	-	2033262..2033459 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
DQM60_RS09550 (NCTC7366_01934)	-	2033710..2034903 (-)	1194	WP_003095894.1	acetate kinase	-
DQM60_RS09555 (NCTC7366_01935)	comYH	2034960..2035916 (-)	957	WP_037601477.1	class I SAM-dependent methyltransferase	Machinery gene
DQM60_RS09560 (NCTC7366_01936)	comGG	2035961..2036278 (-)	318	WP_037601475.1	competence type IV pilus minor pilin ComGG	-
DQM60_RS09565 (NCTC7366_01937)	comYF	2036256..2036693 (-)	438	WP_037601472.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM60_RS09570 (NCTC7366_01938)	comGE	2036680..2036910 (-)	231	WP_084871057.1	competence type IV pilus minor pilin ComGE	-
DQM60_RS09575 (NCTC7366_01939)	comYD	2036942..2037370 (-)	429	WP_269434102.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQM60_RS09580 (NCTC7366_01940)	comYC	2037330..2037644 (-)	315	WP_037611125.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM60_RS09585 (NCTC7366_01941)	comYB	2037653..2038753 (-)	1101	WP_138261574.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM60_RS09590 (NCTC7366_01942)	comGA/cglA/cilD	2038635..2039576 (-)	942	WP_002887018.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM60_RS09595 (NCTC7366_01943)	-	2039610..2041088 (-)	1479	WP_084871058.1	IS1182 family transposase	-
DQM60_RS09600 (NCTC7366_01944)	-	2041218..2041580 (-)	363	WP_049529260.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16198.60 Da
• Isoelectric Point: 8.4658

>NTDB_id=1138803 DQM60_RS09565 WP_037601472.1 2036256..2036693(-) (comYF) [Streptococcus salivarius strain NCTC7366]
MSLNSKVRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVKQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSATDFRKTNADGRGYQPMLFNVKSSTISQNNQIVTIQVTLKNGLQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1138803 DQM60_RS09565 WP_037601472.1 2036256..2036693(-) (comYF) [Streptococcus salivarius strain NCTC7366]
ATGTCTCTAAATAGTAAGGTTCGCGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTGATTGCTGGTTCAGTCCA
AGTTTATCAAGGTCTGACTACAGTATTGGTGAGCAATGTTAAGCAGGTCAAGCAACAAGAAAACCAAGACTGGCTTCTAT
TTGTCCAACAAATGGAGGCAGAATTAGAAGGTTGTCAGTTGGTAAAGGTAGAGGGGAACAAACTCTATGTCAAGCAAGAT
AATCAAGACCTGGCTTTTGGACTCTCAAGTGCGACTGATTTTCGAAAAACAAATGCTGACGGTCGAGGCTACCAACCAAT
GCTTTTCAATGTAAAATCTAGTACGATTAGTCAAAATAACCAGATAGTCACCATCCAAGTGACTCTAAAAAACGGGCTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	57.447	97.241	0.559
comYF	Streptococcus mutans UA159	56.738	97.241	0.552
comGF/cglF	Streptococcus pneumoniae Rx1	50.704	97.931	0.497
comGF/cglF	Streptococcus pneumoniae D39	50.704	97.931	0.497
comGF/cglF	Streptococcus pneumoniae R6	50.704	97.931	0.497
comGF/cglF	Streptococcus pneumoniae TIGR4	50.704	97.931	0.497
comGF/cglF	Streptococcus mitis NCTC 12261	47.917	99.31	0.476
comGF/cglF	Streptococcus mitis SK321	47.917	99.31	0.476
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434