Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   DQM60_RS09555 Genome accession   NZ_LS483366
Coordinates   2034960..2035916 (-) Length   318 a.a.
NCBI ID   WP_037601477.1    Uniprot ID   A0A074IXP5
Organism   Streptococcus salivarius strain NCTC7366     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2029960..2040916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM60_RS09525 (NCTC7366_01929) proC 2030498..2031268 (+) 771 WP_002885846.1 pyrroline-5-carboxylate reductase -
  DQM60_RS09530 (NCTC7366_01930) - 2031295..2031957 (-) 663 WP_111686674.1 CPBP family intramembrane glutamic endopeptidase -
  DQM60_RS09535 (NCTC7366_01931) - 2032070..2032516 (-) 447 WP_013991259.1 hypothetical protein -
  DQM60_RS09540 (NCTC7366_01932) - 2032594..2033250 (-) 657 WP_037601483.1 CPBP family intramembrane glutamic endopeptidase -
  DQM60_RS09545 (NCTC7366_01933) - 2033262..2033459 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  DQM60_RS09550 (NCTC7366_01934) - 2033710..2034903 (-) 1194 WP_003095894.1 acetate kinase -
  DQM60_RS09555 (NCTC7366_01935) comYH 2034960..2035916 (-) 957 WP_037601477.1 class I SAM-dependent methyltransferase Machinery gene
  DQM60_RS09560 (NCTC7366_01936) comGG 2035961..2036278 (-) 318 WP_037601475.1 competence type IV pilus minor pilin ComGG -
  DQM60_RS09565 (NCTC7366_01937) comYF 2036256..2036693 (-) 438 WP_037601472.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM60_RS09570 (NCTC7366_01938) comGE 2036680..2036910 (-) 231 WP_084871057.1 competence type IV pilus minor pilin ComGE -
  DQM60_RS09575 (NCTC7366_01939) comYD 2036942..2037370 (-) 429 WP_269434102.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM60_RS09580 (NCTC7366_01940) comYC 2037330..2037644 (-) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM60_RS09585 (NCTC7366_01941) comYB 2037653..2038753 (-) 1101 WP_138261574.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM60_RS09590 (NCTC7366_01942) comGA/cglA/cilD 2038635..2039576 (-) 942 WP_002887018.1 competence type IV pilus ATPase ComGA Machinery gene

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35775.66 Da        Isoelectric Point: 4.3440

>NTDB_id=1138802 DQM60_RS09555 WP_037601477.1 2034960..2035916(-) (comYH) [Streptococcus salivarius strain NCTC7366]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANEVIIKNNEKLRALDLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTKDDQLDILEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIADVVNSS
AVYIQEDAVRPHILKESDVIISDLPVGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAILLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTENAPETFVYPLSDLQNPEILKDFTDNFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=1138802 DQM60_RS09555 WP_037601477.1 2034960..2035916(-) (comYH) [Streptococcus salivarius strain NCTC7366]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACCATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTAGCTAATGAAGTCATCATCAAAAACAACG
AGAAATTACGTGCTCTTGATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTCTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATTGGATTTATCATTCTTTACCTACTCGAAGGTTTGACCAA
GGACGACCAATTAGATATTTTAGAGATTGGTTCAGGGACAGGAAACTTAGCTGAAACCCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGAATGGAAGTTGACGATCTCCTTATCGATTTGTCAGCTAGTATTGCTGATGTGGTGAATTCAAGT
GCAGTTTACATCCAAGAAGATGCTGTTCGACCACACATTCTCAAAGAGAGTGATGTTATTATCAGTGACCTACCTGTTGG
ATATTACCCAAATGATGAGATTGCGAGTCGTTTCAAGGTTGCAGCAACTGGTGAACACACCTATGCCCATCACCTTCTCA
TGGAGCAATCACTCAAGTACCTGAAGAAAGATGGTATTGCTATTCTTTTGGCACCAACTAATCTTTTGACAAGCCCACAA
AGTGACTTGCTTAAGAAATGGCTATCAGGATATGCTGATATTATTGCCGTTATCACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTCGTGCTTAAAAAACAAACTGAAAATGCTCCAGAGACCTTCGTTTATCCACTTAGCG
ATTTGCAAAACCCAGAGATCCTCAAGGATTTCACAGATAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A074IXP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

70.159

99.057

0.695
  comYH Streptococcus mutans UA140

70.159

99.057

0.695

Multiple sequence alignment