Detailed information NTG1138806

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: DQM60_RS09585
• Genome accession: NZ_LS483366
• Coordinates: 2037653..2038753 (-)
• Length: 366 a.a.
• NCBI ID: WP_138261574.1
• Uniprot ID: A0AAW7PH61
• Organism: Streptococcus salivarius strain NCTC7366
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2039610..2041088	2037653..2038753	flank	857

Gene organization within MGE regions

Location: 2037653..2041088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM60_RS09585 (NCTC7366_01941)	comYB	2037653..2038753 (-)	1101	WP_138261574.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM60_RS09590 (NCTC7366_01942)	comGA/cglA/cilD	2038635..2039576 (-)	942	WP_002887018.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM60_RS09595 (NCTC7366_01943)	-	2039610..2041088 (-)	1479	WP_084871058.1	IS1182 family transposase	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41751.02 Da
• Isoelectric Point: 10.1478

>NTDB_id=1138806 DQM60_RS09585 WP_138261574.1 2037653..2038753(-) (comYB) [Streptococcus salivarius strain NCTC7366]
MPVKISKVIRQPVGTSSWKAWLNKDISLKGISKGKKLKINQQLKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKENWAVQLVQIFPQLFFVILCGLLVLSLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYMTAYYAREWG
NLLGQGIDLLDLVALMKEQKSKLFRELGADLEEALMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QTFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=1138806 DQM60_RS09585 WP_138261574.1 2037653..2038753(-) (comYB) [Streptococcus salivarius strain NCTC7366]
TTGCCAGTGAAAATTTCCAAAGTCATTCGTCAACCAGTTGGAACCAGCAGTTGGAAGGCTTGGTTAAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAACTCAAGGTTATCCAGCTTTTCAAACAACTTTTAA
AGGCAGGGTTTACCTTGACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCCTTGTCTCTTATG
AAAGCGAGTTTAATGCGAGGTGACAGGTTGGACCAGATGTTTGCGTCAGTGGGCTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACTAAGATTGAAACCTACATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATTCTACTTCTGGGTTTCCTGATTCTGATTATGTTGGGGCTCAAAAAT
TATCTTCTGCCTCAACTGTTAGAGGGGGATGGTAAGGAGAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTCTT
TTTTGTGATTTTGTGCGGACTGCTTGTATTAAGCTTAATTCTCTATCTATGGGTGAAACGCCAGTCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTTATAGGCCAAACTGTCAGGCTATATATGACCGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGGCAAGGTATTGACTTGCTAGACTTAGTTGCCCTAATGAAAGAGCAAAAATCAAAGCTCTTTCGTGAGCT
GGGGGCTGATTTAGAAGAAGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTAGTCACCCTTTCTTCACTAAGG
AACTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGACTTTCTTCAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	55.394	93.716	0.519
comYB	Streptococcus mutans UA159	55.394	93.716	0.519
comYB	Streptococcus gordonii str. Challis substr. CH1	51.312	93.716	0.481
comGB/cglB	Streptococcus mitis NCTC 12261	50	92.35	0.462
comGB/cglB	Streptococcus mitis SK321	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae Rx1	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae D39	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae R6	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae TIGR4	49.112	92.35	0.454
comGB	Lactococcus lactis subsp. cremoris KW2	44.985	89.891	0.404