Detailed information NTG1138782

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: DQM60_RS05485
• Genome accession: NZ_LS483366
• Coordinates: 1221842..1222549 (-)
• Length: 235 a.a.
• NCBI ID: WP_002884978.1
• Uniprot ID: A0AB33ZBK5
• Organism: Streptococcus salivarius strain NCTC7366
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1216842..1227549

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM60_RS05460 (NCTC7366_01101)	tnpA	1218113..1218586 (-)	474	WP_013990678.1	IS200/IS605 family transposase	-
DQM60_RS05465	-	1218824..1219101 (-)	278	Protein_1021	ISL3 family transposase	-
DQM60_RS05470 (NCTC7366_01102)	-	1219273..1219632 (-)	360	WP_111686598.1	YbaN family protein	-
DQM60_RS05475 (NCTC7366_01103)	vicX	1219691..1220503 (-)	813	WP_045772120.1	MBL fold metallo-hydrolase	Regulator
DQM60_RS05480 (NCTC7366_01104)	vicK	1220509..1221849 (-)	1341	WP_013990681.1	cell wall metabolism sensor histidine kinase VicK	Regulator
DQM60_RS05485 (NCTC7366_01105)	vicR	1221842..1222549 (-)	708	WP_002884978.1	response regulator YycF	Regulator
DQM60_RS05490 (NCTC7366_01106)	-	1222835..1223602 (+)	768	WP_111686599.1	amino acid ABC transporter ATP-binding protein	-
DQM60_RS05495 (NCTC7366_01107)	-	1223612..1224445 (+)	834	WP_014633206.1	transporter substrate-binding domain-containing protein	-
DQM60_RS05500 (NCTC7366_01108)	-	1224463..1225161 (+)	699	WP_014633207.1	amino acid ABC transporter permease	-
DQM60_RS05505 (NCTC7366_01109)	-	1225173..1225823 (+)	651	WP_002886253.1	amino acid ABC transporter permease	-
DQM60_RS05510 (NCTC7366_01110)	-	1226010..1226777 (+)	768	WP_038675884.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27045.90 Da
• Isoelectric Point: 4.8387

>NTDB_id=1138782 DQM60_RS05485 WP_002884978.1 1221842..1222549(-) (vicR) [Streptococcus salivarius strain NCTC7366]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1138782 DQM60_RS05485 WP_002884978.1 1221842..1222549(-) (vicR) [Streptococcus salivarius strain NCTC7366]
ATGAAAAAAATTCTAGTAGTTGATGATGAAAGACCAATCTCGGATATCATCAAGTTTAATCTGACTAAAGAGGGTTATGA
AGTTGTTACGGCTTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGCTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCAATTATCATGCTTTCCGCT
AAGGATAGCGAGTTCGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACAAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGTA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.687	99.149	0.8
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.559	100	0.387