Detailed information NTG1138781

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: DQM60_RS05480
• Genome accession: NZ_LS483366
• Coordinates: 1220509..1221849 (-)
• Length: 446 a.a.
• NCBI ID: WP_013990681.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain NCTC7366
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1215509..1226849

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM60_RS05450 (NCTC7366_01099)	yidA	1215954..1216760 (+)	807	WP_004182607.1	sugar-phosphatase	-
DQM60_RS05455 (NCTC7366_01100)	-	1216760..1217974 (+)	1215	WP_111686597.1	aminoacyltransferase	-
DQM60_RS05460 (NCTC7366_01101)	tnpA	1218113..1218586 (-)	474	WP_013990678.1	IS200/IS605 family transposase	-
DQM60_RS05465	-	1218824..1219101 (-)	278	Protein_1021	ISL3 family transposase	-
DQM60_RS05470 (NCTC7366_01102)	-	1219273..1219632 (-)	360	WP_111686598.1	YbaN family protein	-
DQM60_RS05475 (NCTC7366_01103)	vicX	1219691..1220503 (-)	813	WP_045772120.1	MBL fold metallo-hydrolase	Regulator
DQM60_RS05480 (NCTC7366_01104)	vicK	1220509..1221849 (-)	1341	WP_013990681.1	cell wall metabolism sensor histidine kinase VicK	Regulator
DQM60_RS05485 (NCTC7366_01105)	vicR	1221842..1222549 (-)	708	WP_002884978.1	response regulator YycF	Regulator
DQM60_RS05490 (NCTC7366_01106)	-	1222835..1223602 (+)	768	WP_111686599.1	amino acid ABC transporter ATP-binding protein	-
DQM60_RS05495 (NCTC7366_01107)	-	1223612..1224445 (+)	834	WP_014633206.1	transporter substrate-binding domain-containing protein	-
DQM60_RS05500 (NCTC7366_01108)	-	1224463..1225161 (+)	699	WP_014633207.1	amino acid ABC transporter permease	-
DQM60_RS05505 (NCTC7366_01109)	-	1225173..1225823 (+)	651	WP_002886253.1	amino acid ABC transporter permease	-
DQM60_RS05510 (NCTC7366_01110)	-	1226010..1226777 (+)	768	WP_038675884.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 446 a.a.
• Molecular weight: 50929.21 Da
• Isoelectric Point: 5.1606

>NTDB_id=1138781 DQM60_RS05480 WP_013990681.1 1220509..1221849(-) (vicK) [Streptococcus salivarius strain NCTC7366]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide

• Length: 1341 bp

>NTDB_id=1138781 DQM60_RS05480 WP_013990681.1 1220509..1221849(-) (vicK) [Streptococcus salivarius strain NCTC7366]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTACATGAGTGATGGAGTCAT
TGCGACAAATCGTCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAAACAGCGA
CTCAGATGTCTATTTTAGATTTATTAGATGGTGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCTAACGATGAGTTTGTGACCTTACGTGTTAACTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCTGTTCTTCACGATGCCACTGAGCAGGAAAAAGAAGAGCGTGAACGTCGACTTTTCGTCTCGA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGAGCTCTCGATGAA
GAGATTGCCCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCACGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAGAGTCAAGAAACCAATACAGGTAAAACTTACGAAATTATTCGAGATTATCCGGTAAACTCAATT
TGGGTAGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCCATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGACTCACAGTTGATCGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCAAGAAGTCGTGCCCAGGGTGGAACTGGTCTT
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAAGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (94-197)

• His Kinase A (phospho-acceptor) domain (HisKA) (208-272)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (325-435)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.671	92.825	0.684
micB	Streptococcus pneumoniae Cp1015	67.667	97.085	0.657