Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM47_RS01485 Genome accession   NZ_LS483360
Coordinates   273354..273905 (+) Length   183 a.a.
NCBI ID   WP_080263242.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC10876     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 268354..278905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM47_RS01485 (NCTC10876_00293) comX/sigX/comX2/sigX2 273354..273905 (+) 552 WP_080263242.1 sigma-70 family RNA polymerase sigma factor Regulator
  DQM47_RS01490 (NCTC10876_00294) truA 274090..274839 (+) 750 WP_002988132.1 tRNA pseudouridine(38-40) synthase TruA -
  DQM47_RS01495 (NCTC10876_00295) - 274829..275593 (+) 765 WP_002988136.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  DQM47_RS01500 (NCTC10876_00296) - 275583..276053 (+) 471 WP_023610570.1 ECF transporter S component -
  DQM47_RS01505 (NCTC10876_00297) - 276067..276627 (+) 561 WP_002995157.1 TIGR01440 family protein -
  DQM47_RS01510 (NCTC10876_00298) - 276692..277537 (-) 846 WP_002982833.1 mechanosensitive ion channel family protein -

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22251.05 Da        Isoelectric Point: 10.1280

>NTDB_id=1138456 DQM47_RS01485 WP_080263242.1 273354..273905(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC10876]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLRLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=1138456 DQM47_RS01485 WP_080263242.1 273354..273905(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC10876]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTACGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.333

81.967

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

46.104

84.153

0.388
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment