Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQL13_RS06980 Genome accession   NZ_LS483354
Coordinates   1475117..1475827 (-) Length   236 a.a.
NCBI ID   WP_012515994.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11606     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1470117..1480827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL13_RS06960 (NCTC11606_01393) - 1470565..1472076 (-) 1512 WP_282731060.1 helix-turn-helix domain-containing protein -
  DQL13_RS06970 (NCTC11606_01394) vicX 1472959..1473768 (-) 810 WP_012515992.1 MBL fold metallo-hydrolase Regulator
  DQL13_RS06975 (NCTC11606_01395) vicK 1473772..1475124 (-) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL13_RS06980 (NCTC11606_01396) vicR 1475117..1475827 (-) 711 WP_012515994.1 response regulator YycF Regulator
  DQL13_RS06985 (NCTC11606_01397) - 1476024..1477043 (-) 1020 WP_012515995.1 DUF3114 domain-containing protein -
  DQL13_RS06990 (NCTC11606_01398) - 1477089..1478351 (-) 1263 WP_012515996.1 AMP-binding protein -
  DQL13_RS06995 (NCTC11606_01399) - 1478341..1479456 (-) 1116 WP_012515997.1 acetyl-CoA C-acyltransferase -
  DQL13_RS07000 (NCTC11606_01400) - 1479453..1479992 (-) 540 WP_012515998.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26981.84 Da        Isoelectric Point: 4.9038

>NTDB_id=1138167 DQL13_RS06980 WP_012515994.1 1475117..1475827(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1138167 DQL13_RS06980 WP_012515994.1 1475117..1475827(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
ATGAAGAAAATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGCTATGA
TACGGTCACAGCCTTTGATGGCAAAGAGGCCGTTGCAGTCTTTGAAGAGGAAAAGCCAGATTTGATTATTTTGGATTTGA
TGCTTCCTGAGCTAGATGGTCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGCCTTGAAATAGGGGCCGATGATTATGTGACTAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCCGAAGAAAATGCCTCCTCAG
GCTCTCAGGAGCTGACCATCGGCAATCTACAGATTTTGCCAGATGCCTTTATTGCTAAAAAGCATGGTCAAGAGGTTGAG
CTGACCCATCGTGAGTTTGAATTGCTGCATCATCTGGCAAACCATATCGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACCGTATGGGGCTACGATTATTTTGGCGATGTCCGAACCGTTGACGTTACTATCCGTCGCCTGCGCGAAAAAATAGAGG
ATACACCGAGTCGTCCAGAGTATATTTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.983

100

0.89
  micA Streptococcus pneumoniae Cp1015

78.112

98.729

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.034

99.153

0.377

Multiple sequence alignment