Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DQL13_RS06975 Genome accession   NZ_LS483354
Coordinates   1473772..1475124 (-) Length   450 a.a.
NCBI ID   WP_014623188.1    Uniprot ID   A0A6M1KZW6
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11606     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1468772..1480124
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL13_RS06955 (NCTC11606_01392) rnc 1469614..1470306 (-) 693 WP_037581642.1 ribonuclease III -
  DQL13_RS06960 (NCTC11606_01393) - 1470565..1472076 (-) 1512 WP_282731060.1 helix-turn-helix domain-containing protein -
  DQL13_RS06970 (NCTC11606_01394) vicX 1472959..1473768 (-) 810 WP_012515992.1 MBL fold metallo-hydrolase Regulator
  DQL13_RS06975 (NCTC11606_01395) vicK 1473772..1475124 (-) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQL13_RS06980 (NCTC11606_01396) vicR 1475117..1475827 (-) 711 WP_012515994.1 response regulator YycF Regulator
  DQL13_RS06985 (NCTC11606_01397) - 1476024..1477043 (-) 1020 WP_012515995.1 DUF3114 domain-containing protein -
  DQL13_RS06990 (NCTC11606_01398) - 1477089..1478351 (-) 1263 WP_012515996.1 AMP-binding protein -
  DQL13_RS06995 (NCTC11606_01399) - 1478341..1479456 (-) 1116 WP_012515997.1 acetyl-CoA C-acyltransferase -
  DQL13_RS07000 (NCTC11606_01400) - 1479453..1479992 (-) 540 WP_012515998.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51527.91 Da        Isoelectric Point: 5.5557

>NTDB_id=1138166 DQL13_RS06975 WP_014623188.1 1473772..1475124(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1138166 DQL13_RS06975 WP_014623188.1 1473772..1475124(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCACAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAATGACCTATCAGAT
GTTTTTCGTCTGACTCATGAAAACCTTGCTCAAGAAAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGCGAGCAGG
CCTTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCCCCTTATACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAACCGTCGTAATGATACAGGAGAATTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTGGTTGTTGTACTTCATGACACGACTGAGCAGGAAAAGGAAGAGCGCGAGCGCAGACTCTTTGTTT
CAAATGTTAGCCATGAGCTGCGGACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATCGCTCCAAGCTTTATAAAGGTCTCACTAGATGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
CCTCTCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCCATTACCTCT
ATTTGGCTAGAAATTGACAATGACAAAATGACGCAGGTTATCGAAAATATTTTAAACAATGCGATCAAATATTCACCCGA
TGGCGGAAAAATTGTCGTCAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGCTTGGGTATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGGAGTAGAGCTCAAGGAGGGACCGGG
CTAGGCCTAGCGATTGCTAAAGAAATTATTAAGCAGCACCGAGGCTTTATTTGGGCTAAGAGTGATTATGGCAAGGGCTC
AACCTTTACCATTGTGTTACCTTATGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M1KZW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631

Multiple sequence alignment