Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM42_RS01720 Genome accession   NZ_LS483351
Coordinates   302027..302578 (+) Length   183 a.a.
NCBI ID   WP_079993350.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8195     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 297027..307578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM42_RS01720 (NCTC8195_00347) comX/sigX/comX2/sigX2 302027..302578 (+) 552 WP_079993350.1 competence protein ComX Regulator
  DQM42_RS01725 (NCTC8195_00348) - 303137..303664 (+) 528 WP_002991099.1 YqeG family HAD IIIA-type phosphatase -
  DQM42_RS01730 (NCTC8195_00349) yqeH 303664..304782 (+) 1119 WP_002985994.1 ribosome biogenesis GTPase YqeH -
  DQM42_RS01735 (NCTC8195_00350) yhbY 304808..305116 (+) 309 WP_002991094.1 ribosome assembly RNA-binding protein YhbY -
  DQM42_RS01740 (NCTC8195_00351) - 305185..305817 (+) 633 WP_002991091.1 nicotinate-nucleotide adenylyltransferase -
  DQM42_RS01745 (NCTC8195_00352) yqeK 305814..306407 (+) 594 WP_002985989.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DQM42_RS01750 (NCTC8195_00353) rsfS 306431..306784 (+) 354 WP_011017339.1 ribosome silencing factor -
  DQM42_RS01755 (NCTC8195_00354) - 306832..307575 (+) 744 WP_032467300.1 class I SAM-dependent DNA methyltransferase -

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22297.08 Da        Isoelectric Point: 10.0375

>NTDB_id=1137981 DQM42_RS01720 WP_079993350.1 302027..302578(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC8195]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVSYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=1137981 DQM42_RS01720 WP_079993350.1 302027..302578(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC8195]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGTCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

45.455

84.153

0.383
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment